右咪托咪定麻醉对老年食管癌根治术后患者麻醉恢复期应激反应的影响  

Effect of Dexmetomidine Anesthesia on Stress Response of Elderly Patients after Radical Resection of Esophageal Cancer During the Recovery Period of Anesthesia

作　　者：林绍立[1] 林梁[1] 洪甲庚[1] 王庆祥[1] LIN Shaoli;LIN Liang;HONG Jiageng(First Affiliated Hospital of Xiamen University,Xiamen 361003,China)

机构地区：[1]厦门大学附属第一医院,福建厦门361003

出　　处：《中外医学研究》2018年第27期14-15,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨右咪托咪定麻醉对老年食管癌根治术后患者麻醉恢复期应激反应影响。方法:对2016年1月-2017年12月在笔者所在医院治疗的32例老年食管癌患者随机分组,对照组患者注射生理盐水治疗,试验组患者给予右咪托咪定治疗,观察比较两组患者VAS评分、E和NE浓度差异。结果:试验组患者术后8、12、24、48 h时VAS评分均明显低于对照组,差异均有统计学意义(P<0.05)。试验组患者T0、T1、T2、T3、T4各点E和NE水平较对照组均明显下降,差异均有统计学意义(P<0.05)。结论:针对老年食管癌根治术患者应用右咪托咪定麻醉可降低麻醉恢复期应激反应,提高镇痛效果,值得推广应用。Objective：To investigate the effect of Dexmetomidine Anesthesia on stress response of elderly patients after radical resection of esophageal cancer.Method：From January 2016 to December 2017,32 elderly patients with esophageal cancer were randomly divided into two groups：the control group was treated with normal saline and the patients in the experimental group were treated with dexmidine.The difference of E and NE in VAS score between the two groups was observed and compared.Result： The VAS scores in the trial group were significantly lower than those in the control group at 8,12,24,48 hours after operation,the differences were statistically significant （P〈0.05）.The levels of E and NE in T0,T1,T2,T3,T4 in the trial group were significantly lower than those in the control group,the differences were statistically significant （P〈0.05）.Conclusion： Dexmetomidine Anesthesia can reduce stress response and improve analgesic effect in the recovery period of elderly patients with esophageal cancer.It is worth popularizing.

关 键 词：右咪托咪定 老年食管癌根治术 麻醉恢复期 应激反应 

分 类 号：R735.1[医药卫生—肿瘤]