丹参注射液联合醒脑静治疗高血压性脑出血临床观察  

Clinical Observation on Danshen Injection Combined with Xingnaojing Injection for Hypertensive Cerebral Hemorrhage

作　　者：杨峰[1] 王勇 YANG Feng;WANG Yong

机构地区：[1]绍兴市人民医院神经内科,浙江绍兴312000 [2]绍兴市上虞人民医院检验科,浙江绍兴312300

出　　处：《新中医》2018年第9期52-54,共3页New Chinese Medicine

摘　　要：目的:观察丹参注射液联合醒脑静治疗高血压性脑出血的临床疗效,及对患者血肿体积和神经功能的影响。方法:选取64例高血压性脑出血患者,随机分为观察组和对照组各3 2例。对照组采用常规疗法配合醒脑静注射液治疗,观察组在对照组基础上加用丹参注射液。比较2组患者治疗7天、治疗14天后的血肿体积、美国国立卫生研究院卒中量表(NIHSS)评分以及治疗总有效率。结果:治疗前,2组血肿体积比较无统计学差异(P>0.0 5)。治疗7天及14天,2组血肿体积均较治疗前缩小(P<0.0 5),观察组血肿体积均小于同期对照组(P<0.0 5)。治疗前,2组NIHSS评分比较,差异无统计学意义(P>0.0 5),治疗7天及14天,2组NIHSS评分均较治疗前下降(P<0.0 5),观察组较对照组下降更明显(P<0.0 5)。观察组治疗总有效率90.63%,对照组治疗总有效率65.63%,2组比较,差异有统计学意义(P<0.0 5)。结论:丹参注射液联合醒脑静治疗高血压性脑出血,可促进血肿吸收,改善神经功能。Objective： To observe the clinical effect of Danshen injection combined with Xingnaojing injection for hypertensive cerebral hemorrhage and its effect on hematoma volume and nerve function of patients. Methods： Selected 64 cases of patients with hypertensive cerebral hemorrhage,and divided them into the observation group and the control group randomly,32 cases in each group.The control group received routine therapy combined with Xingnaojing injection for treatment,while the observation group additionally received Danshen injection based on the treatment of the control group. Compared the hematoma volume, scores of the national institutes of health stroke scale（NIHSS） and the total effective rate in the two groups after 7 days and 14 days of treatment. Results：Before treatment,no significant difference was found in the comparison of the hematoma volume between the two groups（P〈0.05）. After7 days and 14 days of treatment,the hematoma volume in the two groups was decreased when compared with that before treatment（P〈0.05）; the hematoma volume in the observation group was smaller than that in the control group during the same period（P〈0.05）.Before treatment,no significant difference was found in the comparison of the NIHSS score between the two groups（P〈0.05）. After 7 days and 14 days of treatment,NIHSS scores in the two groups were decreased when compared with those before treatment（P〈0.05）,and the decrease in the observation group was more obvious than that in the control group（P〈0.05）. The total effective rate was 90.63%in the observation group and was 65.63% in the control group, the difference being significant（P〈0.05）. Conclusion： Danshen injection combined with Xingnaojing injection for patients with hypertensive cerebral hemorrhage can promote the hematoma absorption and improve nerve function.

关 键 词：高血压性脑出血 丹参注射液 醒脑静注射液 血肿体积 神经功能 

分 类 号：R743.3[医药卫生—神经病学与精神病学]