柴芍六君汤加减治疗肝郁脾虚型反流性食管炎临床观察  

Clinical Observation of Modified Chaishao Liujun Tang for Reflux Esophagitis of Liverdepression and Spleen-deficiency Type

作　　者：丁炎萍[1] 方悦[1] 刘丽琴[1] 黄芳[1] 金苏霞[1] DING Yanping;FANG Yue;LIU Liqin;HUANG Fang;JIN Suxia

机构地区：[1]杭州市红十字会医院,浙江杭州310003

出　　处：《新中医》2018年第9期76-78,共3页New Chinese Medicine

摘　　要：目的:探究柴芍六君汤加减治疗肝郁脾虚型反流性食管炎的临床疗效。方法:选择肝郁脾虚型反流食管炎患者90例,随机分为对照组和观察组各45例。对照组给予泮托拉唑肠溶胶囊治疗,观察组给予柴芍六君汤加减治疗。治疗8周后,比较2组的临床疗效、中医证候评分及食管黏膜病变程度改变情况。结果:治疗后,总有效率观察组为95.56%,对照组为77.78%,2组比较,差异有统计学意义(P<0.0 5)。治疗后,2组中医证候评分和食管黏膜病变等级均较治疗前降低(P<0.0 5),观察组中医证候评分和食管黏膜病变等级均较对照组降低更明显(P<0.0 5)。结论:柴芍六君汤加减治疗肝郁脾虚型反流性食管炎作用效果显著,可以明显缓解临床症状,改善患者食管黏膜病变程度。Objective：To discuss the clinical effect of modified Chaishao Liujun tang for reflux esophagitis of liver-depression and spleen-deficiency type. Methods： Selected 90 cases of patients with reflux esophagitis of liver-depression and spleen-deficiency type,and divided them into the control group and the observation group randomly, 45 cases in each group. The control group was given pantoprazole enteric-coated capsules,while the observation group was given modified Chaishao Liujun tang. After 8 weeks of treatment,compared the clinical effect, Chinese medicine syndrome scores and changes of lesion degree in esophageal mucosa of both groups.Results： After treatment, the total effective rate was 95.56% in the observation group and 77.78% in the control group, difference being significant（P〈0.05）. After treatment, Chinese medicine syndrome scores and the lesion degree in esophageal mucosa in both groups were lower than those before treatment（P〈0.05）,and Chinese medicine syndrome scores and the lesion degree in esophageal mucosa in the observation group were decreased more significantly than those in the control group（P〈0.05）. Conclusion： Modified Chaishao Liujun tang for reflux esophagitis of liver-depression and spleen-deficiency type has significant therapeutic effect in relieving the clinical symptoms and improving the lesion degree in esophageal mucosa of patients.

关 键 词：反流性食管炎 肝郁脾虚 柴芍六君汤 泮托拉唑肠溶胶囊 食管黏膜病变 

分 类 号：R571[医药卫生—消化系统]