吸毒对外周血生化指标、BMI及血压的影响分析  

Effect of drug abuse on biochemical indexes of peripheral blood BMI and blood pressure

作　　者：刘环 张伟[2] 邓小冬[2] 马英[3] 刘云[2] LIU Huan;ZHANG Wei;DENG Xiaodong;MA Ying;LIU Yun(Department of Preventive Medicine,North Sichuan Medical College,Nanchong,Sichuan,637000,China;Department of Forensic Medicine,North Sichuan Medical College,Nanchong,Sichuan,637000,China;Department of Neurology,Affiliated Hospital of North Sichuan Medical College,Nanchong,Sichuan,637000,China)

机构地区：[1]川北医学院预防医学系,南充637000 [2]川北医学院法医学系,南充637000 [3]川北医学院附属医院神经内科,南充637000

出　　处：《中国药物依赖性杂志》2018年第4期267-271,共5页Chinese Journal of Drug Dependence

基　　金：国家自然科学基金(81400966);南充市校战略合作课题(NSMC20170440和NSMC20170441);川北医学院科研发展计划项目(CBY-A-YB09)资助

摘　　要：目的:探讨吸毒人群外周血生化指标、BMI及血压的变化情况,并分析其影响因素。方法:收集2015年3月至2016年3月进入南充市强制戒毒所的675名男性吸毒人员的人口学特征、吸毒情况等和同一时期从川北医学院附属医院体检中心选取的554名对照者的人口学特征,测量研究对象的外周血生化指标、身高、体重和血压值并进行统计分析。结果:毒品依赖者的红细胞计数、血红蛋白、BMI及舒张压明显低于对照组,而白细胞计数和收缩压明显高于对照组,差异均有统计学意义(P<0.05)。多重线性回归分析结果显示:毒品依赖者血红蛋白量与滥用时间和每日吸毒量有关;BMI与婚姻情况、滥用时间有关;收缩压与滥用时间有关,均有统计学意义(P<0.05)。结獉论獉:吸毒可能导致人体生理生化指标改变,影响人体健康,毒品依赖者应认识到吸毒的危害,积极进行戒毒治疗。Objective： Objective to investigate the changes of peripheral blood biochemical indicators,BMI and blood pressure in drug users,analyze the influencing factors.Methods： A total of 675 male drug addicts who entered Nanchong compulsory drug treatment center were recruited between March 2015 to March 2016 and gather information on sociocharacteristics and drug abuse status. Meanwhile,a number of 554 controls＇ information on sociocharacteristics were collected from the physical examination center of the affiliated Hospital of North Sichuan Medical College in the same period. We measured peripheral blood biochemical indexes,height,weight,blood pressure and carry out statistical analysis.Results： The RBC of drug addicts,HGB,BMI and diastolic blood pressure was lower than control group. while the WBC and systolic pressure was higher than control group,the difference was statistically significant（ P〈0. 05）. The results of multiple linear regression analysis showed that the HGB of drug addicts was related to the toxic age and daily dose; BMI was related to marital status and toxic age; systolic pressure wasrelated to toxic age,all had statistical significance（ P〈0. 05）.Conclusion： Drug abuse may lead to changes in physiological and biochemical indicators of the human body and affect human health. Drug addicts should recognize the harm of drug use and actively quit drugs.

关 键 词：毒品依赖者 外周血生化指标 BMI 血压 影响因素 

分 类 号：R749.64[医药卫生—神经病学与精神病学]