阴虚证、水肿证、阴虚水肿证中医动物模型的造模方法及评价  

Evaluation and Modeling Methods of "Yin Deficiency" and "Edema" as well as "Yin Deficiency Edema" in Traditional Chinese Medicine

作　　者：徐文峰[1] 范元硕 何泽云[1] 唐群 彭亚军[1] 李旭华[1] XU Wenfeng1, FAN Yuanshuo2, HE Zeyun1, TANG Qun2, PENG Yajun1, LI Xuhua1(1. Department of Nephrology, the First Affiliated Hospital of Hunan University of Chinese Medicine, Hunaaa Province, Changsha 410000, China; 2. Graduate School, Hunan University of Chinese Medicine, Hunan Province, Changsha 410000, China; 3. Medical College, Hunan University of Chinese Medicine, Hunan Province, Changsha 410000, China)

机构地区：[1]湖南中医药大学第一附属医院肾脏内科 [2]湖南中医药大学研究生院 [3]湖南中医药大学医学院

出　　处：《中国中医药现代远程教育》2018年第19期51-53,共3页Chinese Medicine Modern Distance Education of China

基　　金：湖南省教育厅科学研究(优秀青年项目)资助项目【No.15B177】

摘　　要：目的总结近年来中医阴虚、水肿证动物模型的造模方法及检测方法,为中医阴虚水肿证动物模型的建立提供思路与借鉴。方法从中医病因病机、西医病因病理角度探讨及评价阴虚、水肿证的动物模型。结果中医病因病机为指导的动物模型接近中医证候实际,但稳定性、可重复性差,西医病因病理为指导的动物模型稳定性高、可重复性强,但与中医证候实际吻合度欠佳。结论中医病因病机指导下结合西医病因病机的病证结合动物模型是相对理想的中医阴虚水肿证动物模型。Objective To summarize the modeling methods and detection methods of animal models of ＂ yin deficiency＂ and ＂ edema＂ in recent years, providing ideas and reference for the establishment of animal model of TCM ＂ yin deficiency edema＂ . Methods The animal models of ＂ yin deficiency＂ and ＂ edema＂ were discussed and evaluated from the etiology and pathogenesis of traditional Chinese medicine and the etiology and pathology of Western medicine. Results The animal model guided by the etiology and pathogenesis of traditional Chinese medicine is close to the practice of TCM syndrome, but the stability and repeatability are poor. The animal model with the guidance of the etiology and pathology of Western medicine is high and repeatable, but it is not in good agreement with the TCM syndrome. Conclusion Under the guidance of the etiology and pathogenesis of TCM, the animal model combining disease and syndrome with the etiology and pathogenesis of Western medicine is an ideal animal model of ＂ yin deficiency and edema＂ in TCM.

关 键 词：阴虚证 水肿证 阴虚水肿证 动物模型 

分 类 号：R-332[医药卫生] R277.5