甲状腺乳头状癌颈部中央区淋巴结转移数目对颈侧区淋巴结转移的预测价值  

The predictive value of number of central cervical lymph nodes with metastasis for prediction of metastasis in lateral cervical region lymph nodes of patients with thyroid papillary carcinoma

作　　者：刘青[1] 张海军[2] 秦树光[1] LIU Qing;ZHANG Hai-jun;QIN Shu-guang(Department of Nuclear Medicine Discipline;Department of Surgery, Jizhong Energy Summit Group General Hospital, Handan Hebei 056200, China.)

机构地区：[1]冀中能源峰峰集团总医院核医学科,河北邯郸056200 [2]冀中能源峰峰集团总医院外一科,河北邯郸056200

出　　处：《临床和实验医学杂志》2018年第20期2214-2217,共4页Journal of Clinical and Experimental Medicine

基　　金：河北省卫计委科研项目(编号:20150824)

摘　　要：目的探讨甲状腺乳头状癌颈部中央区淋巴结转移数目对颈侧区淋巴结转移的预测价值。方法回顾性分析2014年9月至2017年8月冀中能源峰峰集团总医院病理学检查确诊的131例甲状腺乳头状癌患者的病例资料,患者均行颈部中央区与颈侧区淋巴结清扫手术,统计颈部中央区淋巴结转移数目及其与颈侧区淋巴结转移的关系。结果颈部中央区淋巴结转移对颈侧区淋巴结转移的预测敏感度为65.93%,阳性预测值为66.67%。颈部中央区淋巴结转移数目的增加与颈侧区淋巴结转移率呈正相关(r=0.947,P=0.002)。以2、3、4枚为临界,颈部中央区淋巴结转移患者的颈侧区淋巴结转移率明显升高(P<0.05)。以5、6枚为临界,颈部中央区淋巴结转移患者的颈侧区淋巴结转移率无明显变化(P>0.05)。结论甲状腺乳头状癌患者颈部中央区淋巴结转数目对颈侧区淋巴结转移有较高的预测价值。Objective To explore the predictive value of metastasis in central cervical lymph nodes for metastasis in lateral cervical region lymph nodes in patients with papillary thyroid carcinoma. Methods A retrospective analysis was carried out in 131 cases of thyroid papillary carcinoma confirmed by pathological diagnosis in this hospital during September 2014 to August 2017 had been carried out. The clinical data of these patients with central cervical lymph node dissection, statistical analysis on the relationship between central cervical lymph node metastasis and the number of neck lymph nodes with metastasis. Results The sensitivity of prediction of metastasis in central neck lymph nodes was 65.93% for neck lymph nodes, and its positive predictive value was 66.67%. The increase in transference rate was positively correlated with the number of neck lymph nodes with metastasis （ r =0.947, P =0.002）. As 2, 3 and 4 for critical points, metastasis in central cervical lymph nodes in patients with cervical lymph node metastasis increased significantly （ P 〈0.05）. As 5 and 6 for critical point, metastais in central cervical lymph nodes in patients with cervical lymph node metastasis rate had no significant change （ P 〉0.05）. Conclusion In patients with papillary thyroid carcinoma having metastasis in cervical lymph nodes, the number of neck lymph nodes with metastasis has higher predictive value.

关 键 词：甲状腺乳头状癌 颈部中央区淋巴结转移 数目 颈侧区淋巴结转移 预测 

分 类 号：R736.1[医药卫生—肿瘤]