胞磷胆碱钠联合肌电生物反馈对血管性痴呆患者MMSE评分及日常生活能力的影响  

Effect of Citicoline Sodium combined with electromyographic biofeedback on MMSE score and activity of daily living in patients with vascular dementia

作　　者：褚全红 CHU Quan-hong(Department of Neurology,The People＇s of Yumeng County,Yumeng 432500,China)

机构地区：[1]云梦县人民医院神经内科,432500

出　　处：《中国实用医药》2018年第25期7-9,共3页China Practical Medicine

摘　　要：目的探讨胞磷胆碱钠联合肌电生物反馈对血管性痴呆(VD)患者简易智力状态检查量表(MMSE)评分及日常生活能力的影响。方法 108例VD患者,按照抽签法分为对照组与观察组,每组54例。两组均予以调脂、降压、控制血糖、抗血小板聚集、抗动脉硬化等常规治疗,在此基础上对照组采取胞磷胆碱钠治疗,观察组采取胞磷胆碱钠联合肌电生物反馈治疗。观察两组治疗效果与治疗前、治疗6个月后认知功能状况、日常生活能力状况及生活质量。结果观察组治疗总有效率为77.78%,高于对照组的57.41%,差异有统计学意义(P<0.05);治疗前,两组患者MMSE、Barthel指数评定量表(BI)、健康调查简表(SF-36)评分比较差异无统计学意义(P>0.05),治疗6个月后,两组患者MMSE、BI、SF-36评分均较本组治疗前提高,且观察组高于对照组,差异有统计学意义(P<0.05)。结论 VD患者予以胞磷胆碱钠联合肌电生物反馈治疗能明显增强疗效,提高患者认知功能,提升其日常生活能力与生活质量。Objective To investigate the effect of Citicoline Sodium combined with electromyographic biofeedback on mini-mental state examination （MMSE） score and activity of daily living in patients with vascular dementia （VD）. Methods A total of 108 VD patients were control group and observation group according to the drawing method, 54 cases in each group. The two groups were given routine treatment such as lipid regulation, blood pressure lowering, control blood glucose level, anti-ptatelet aggregation and anti-atherosclerosis. On this basis, the control group received Citicoline Sodium for treatment, the observation group received Citicoline Sodium combined with electromyographic biofeedback for treatment. The treatment effect, cognitive function, daily living ability and quality of life between the two groups were observed before treatment and 6 months after treatment. Results The total effective rate of the observation group was 77.78%, which was significantly higher than 57.41% of the control group （P〈0.05）. Before treatment, there were no significant differences in the MMSE, Barthel index rating scale （BI） and the MOS item short from health survey （SF-36） scores between the two groups （P〉0.05）. After 6 months of treatment, the scores of MMSE, BI and SF-36 in the two groups were significantly higher than those before treatment, and the scores in the observation group were significantly higher than those in the control group, the differences were statistically significant （P〈0.05）. Conclusion Citicoline Sodium combined with electromyographic biofeedback can significantly enhance the efficacy of VD patients, improve cognitive function, elevate their ability of daily living and quality of life.

关 键 词：胞磷胆碱钠 肌电生物反馈 血管性痴呆 

分 类 号：R749.13[医药卫生—神经病学与精神病学]