喉癌患者认知功能特征研究  

Features of cognitive function in patients with laryngeal carcinoma

作　　者：宋开艳[1] 徐勇[2] 高伟[3] 郝文天 姚景春[4] 王磊[1] 蒋宏 高泽慧 王雪瑞 王斌全[3] SONG Kaiyan;XU Yong;GAO Wei;HAO Wentian;YAO Jingchun;WANG Lei;JIANG Hong;GAO Zehui;WANG Xuerui;WANG Binquan(Shanxi Medical University,Taiyuan,030001,China;Department of Psychiatry,the First Hospital,Shanxi Medical University MDT Center for Cognitive Impairment and Sleep Disor-ders,the First Hospital,Shanxi Medical University;Department of Otolaryngology Head and Neck Surgery,the First Hospital,Shanxi Medical University;Shanxi Key Laboratory of Oto-rhinolaryngology Head and Neck Cance;4Department of Otolaryngology Head and Neck Sur-gery,Shanxi Tumor Hospita)

机构地区：[1]山西医科大学,太原030001 [2]山西医科大学第一医院精神卫生科山西医科大学第一医院认知障碍与睡眠障碍多学科诊疗中心 [3]山西医科大学第一医院耳鼻咽喉头颈外科耳鼻咽喉头颈肿瘤山西省重点实验室 [4]山西省肿瘤医院耳鼻咽喉头颈外科

出　　处：《临床耳鼻咽喉头颈外科杂志》2018年第18期1396-1399,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：山西省头颈部恶性肿瘤精准诊疗重点科技创新平台专项(No:201605D151003);山西医科大学大学生创新创业校级项目(No:20160902);山西医科大学第一医院杰出优秀青年基金培育项目(No:YR1601);山西省优秀人才科技创新项目(No:201605D211029)

摘　　要：目的:研究喉癌患者与健康志愿者认知功能的差异。方法:以山西省两所三级甲等医院耳鼻咽喉头颈外科首发的喉癌患者和招募的同年龄(±3岁)、性别匹配以及文化程度相近的健康志愿者为研究对象,以韦氏记忆量表为研究工具,评估研究对象的认知现状。结果:喉癌组与对照组在年龄、性别与文化程度上无显著性差异(P>0.05);喉癌组的记忆商评分比对照组低,差异有统计学意义(P<0.05);喉癌组与对照组在韦氏记忆量表中除经历、定向、联想测验外,其余测验结果都有显著性差异(P<0.05)。结论:喉癌患者在记忆力(如长时记忆、短时记忆、瞬时记忆)、注意力(如图片、再认、触觉)及计算力(如心智积累)方面比同年龄(±3岁)、性别匹配以及文化程度相近的健康志愿者差,喉癌患者表现出认知功能损害或者低下,是患者康复过程中应重视的恢复环节。癌症相关认知障碍的早期发现有助于帮助癌症患者早期改善认知功能,减轻家属及社会负担,促进患者更好地回归社会。Objective：To study the differences in cognitive function between patients with laryngeal carcinoma and healthy volunteers.Method：Patients with laryngeal carcinoma who have been first diagnosed with laryngeal carcinoma,but not received treatment at the Department of Otolaryngology in two hospitals in Shanxi Province and healthy volunteers of the same age,gender-matched and similar education were studied for the purpose to evaluate the cognitive status by using the Wechsler memory scale.Result：No significant difference of age,gender and educational level was found between both groups（P〉0.05）.The score of Memory Quotient was significantly lower in the laryngeal carcinoma group than that in healthy control group（P〈0.05）.There were significant differences in the results of Wechsler memory scale except for Experience,Orientation and Association test（P〈0.05）.Conclusion：The memory,attention and computing power of patients in the laryngeal carcinoma group were not as good as those of patients in the healthy control group.Patients with laryngeal carcinoma have cognitive impairment or lower ability,so we need to pay more attention to the patients during their rehabilitation.The early detection of cancer-related cognitive impairments can help patients improve their cognitive function early,reduce the burden on their families and society,and promote better return of patients to society.

关 键 词：喉肿瘤 癌症相关认知障碍 认知功能 

分 类 号：R739.65[医药卫生—肿瘤]