结膜骨性迷离瘤的临床病理特征分析  

Clinicopathological study on conjunctival osseous choristoma

作　　者：赵云[1] 李浩晴 赵红[1] 林锦镛[1] Zhao Yun;Li Haoqing;Zhao Hong;Lin Jinyong(Tianjin Eye Hospital and Institute,Clinical College of Ophthalmology of Tianjin Medical University,Tianfin Key Laboratory of Ophthalmology and Vision Science,Tianfin 300020,China)

机构地区：[1]天津市眼科医院天津医科大学眼科临床学院天津市眼科研究所天津市眼科学与视觉科学重点实验室,300020

出　　处：《中华眼科杂志》2018年第9期661-664,共4页Chinese Journal of Ophthalmology

摘　　要：目的总结结膜骨性迷离瘤的临床和病理学特点。方法回顾性系列病例研究。收集天津市眼科医院自2009年1月至2016年6月间确诊的6例结膜骨性迷离瘤患者的临床资料，分析其影像学、病理学检查结果。结果6例患者中，男性3例，女性3例，年龄4-20岁。肿瘤位于右眼3例，左眼3例。主要表现为球结膜颞上象限扁平状隆起肿物。CT检查表现为眼球表面椭圆形钙斑。6例患者均经手术治疗，病理学检查可见肿瘤由骨组织组成，周围有薄层纤维组织包绕，骨组织中含有哈弗管结构。其中5例患者随访23个月至8年均未见复发。结论结膜骨性迷离瘤以结膜颞上象限肿物为主要表现，影像学检查以眼球表面椭圆形高密度钙化影为特征，病理学检查以由成熟密质骨组织组成、周围包绕有纤维组织的骨性肿瘤为特征，骨组织中含有典型的哈弗管结构。确诊有赖于组织病理学检查，手术完整切除后一般不易复发。（中华腠科杂志，2018，54：661．664）Objective To summarize the clinical pathologic characteristics of conjunctival osseous ehoristoma. Methods Retrospective case series study. Six cases of conjunetival osseous choristoma between January 2009 and June 2016 from Tianjin Eye Hosptial were reviewed retrospectively. The clinical features, CT characteristics and histological characteristics were analyzed. Results The 6 cases includes 3 male patients and 3 females. The age of the patients ranged from 4 to 20 years. Three cases involved with the fight eye and the other 3 involved with the left eye. Major clinical feature of the patient is the flat uplift tumor in the superior temporal quadrant of the conjunctiva. CT features of conjunctival osseous choristoma revealed a oval calcium spot of eyeball surface. All the patients received surgery. Pathological examination showed that the tumor is composed of bone tissue which was surrounded by fibrous tissue, and Haversian canals are present in compact bone tissue. Five patients were followed for 23 months to 8 years. None of the patients relapsed after operation. Conclusions The major feature of conjuncital osseous choristoma is a tumor in the superior temporal quadrant of conjunctiva. Imaging examination reveals a oval calcium spot of eyeball surface. Pathological examination reveals that the osseous tumor is composed of compact bone tissue which was surrounded by fibrous tissue. Haversian canals are present in compact bone tissue. Diagnosis is dependent on histopathological examination. It is not prone to relapse after complete resection surgery. （Chin J Ophthalmol, 2018, 54： 661-664）

关 键 词：骨和骨组织 迷芽瘤 眼肿瘤 结膜疾病 

分 类 号：R739.7[医药卫生—肿瘤]