释氟高流动树脂在儿童早期釉质龋窝沟封闭中的应用  

Application of fluoride releasing flowable resin in pit and fissure sealant of children with early enamel caries

作　　者：闫文娟 郑佳佳[1] 陈小贤[1] YAN Wen-juan;ZHENG Jia-jia;CHEN Xiao-xian(First Clinical Division,Peking University School and Hospital of Stomatology ＆ National Clinical Research Center for Oral Diseases ＆ National Engineering Laboratory for Digital and Material Technology of Stomatology ＆ Beijing Key Laboratory of Digital Stomatology,Beijing 100034,China)

机构地区：[1]北京大学口腔医学院.口腔医院门诊部国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室,北京100034

出　　处：《北京大学学报（医学版）》2018年第5期911-914,共4页Journal of Peking University:Health Sciences

摘　　要：目的:评价释氟高流动性树脂对儿童恒牙早期釉质龋进行窝沟封闭的临床应用效果,并与传统窝沟封闭剂做对比。方法:临床纳入76名儿童,共52对第一恒磨牙和30对恒前磨牙,双侧同名牙均根据国际龋齿检测与评估系统(International Caries Detection and Assessment System,ICDAS)龋齿诊断标准诊断为早期釉质龋,采取自身双侧对照研究方法,随机选择一侧恒牙作为实验组,使用释氟高流动性树脂进行窝沟封闭,对侧同名牙作为对照组,使用传统窝沟封闭剂,在3、6、12、24个月进行临床观察比较,评价窝沟封闭剂的保存率和龋齿的进展情况。结果:使用释氟高流动树脂及传统窝沟封闭剂对恒前磨牙进行窝沟封闭后3个月和6个月均无封闭剂脱落和龋齿进展,12个月和24个月对照组各有1例发生封闭剂脱落,差异无统计学意义。第一恒磨牙实验组在封闭后3、6、12和24个月封闭剂完全保存率分别为100%、98.08%、90.38%和88.46%,而传统窝沟封闭组分别为96.15%、92.31%、76.92%和73.08%,封闭后24个月实验组封闭剂完全保存率明显高于对照组,差异有统计学意义(P<0.05)。封闭后6、12和24个月实验组龋齿进展率分别为1.92%、5.77%和7.69%,对照组分别为5.77%、19.23%和25.00%,12个月及24个月时实验组龋齿进展率明显低于对照组(P<0.05)。结论:与传统窝沟封闭剂相比,采用释氟高流动性树脂对儿童恒磨牙早期釉质龋窝沟封闭可以提高窝沟封闭剂保存率,且能有效阻止龋齿发展。Objective： To evaluate the clinical effect of fluoride releasing flowable resin used in treatment of early enamel caries of children compared with conventional sealant. Methods： Seventy-six patients,including fifty-two couples of permanent first molars and thirty couples of premolars were selected for this trial. Both sides of all the molars and premolars were diagnosed as early enamel caries based on International Caries Detection and Assessment System （ICDAS） dental caries diagnostic criteria. Using the contralateral control,the teeth were randomly divided into two groups. Molars/premolars in the experimental group were sealed with a fluoride releasing flowable resin; the contralateral molars/premolars were sealed with a conventional fissure sealant as a control group. The retention rate and progress of caries were evaluated at the end of 3,6,12 and 24 months. Results： There was no fissure sealant loss or caries progression in both groups 3 and 6 months after sealing the premolars by fluoride releasing flowable resin or conventional fissure sealants. At the end of 12 and 24 months,only one case of fissure sealant loss was observed in conventional fissure sealant group. There was no statistical significance between the two premolar groups. In the first molar group,fluoride releasing flowable resin showed 100%,98. 08%,90. 38% and 88. 46% complete retention at the end of 3,6,12 and 24 months,respectively. The conventional fissure sealant retention rates were 96. 15%,92. 31%,76. 92% and 73. 08% at the corresponding time points. The data at the end of 24 months showed that fluoride releasing flowable resin had significantly higher retention rate than the conventional fissure sealant group （P 〈0. 05）. The incidence of caries progression at the end of 6,12 and 24 months were 1. 92%,5. 77% and 7. 69%,respectively,in the fluoride releasing flowable resin group. In the conventional fissure sealant group,the incidence was5. 77%,19. 23% and 25. 00%,respectively. At the end of 12 and 24 months,more significa

关 键 词：龋齿 牙釉质 窝沟封闭剂 流动树脂 

分 类 号：R788.1[医药卫生—口腔医学]