急性缺血性脑卒中溶栓治疗的临床应用效果观察  

Clinical effect of thrombolytic therapy for acute ischemic stroke

作　　者：邝俊 李霖[1] Kuang Jun;Li Lin(Emergency Department,the First People＇s Hospital of Chenzhou City Hunan Province 42300)

机构地区：[1]湖南省郴州市第一人民医院急诊科,423000

出　　处：《中国社区医师》2018年第27期64-65,共2页Chinese Community Doctors

摘　　要：目的:探讨急性缺血性脑卒中溶栓治疗的临床效果。方法:收治急性缺血性脑卒中患者124例,分为3组,对照组37例,尿激酶组41例,rt-PA组46例。对照组急性缺血性脑卒中患者采用常规治疗,尿激酶组急性缺血性脑卒中患者在常规治疗基础上加用尿激酶静脉溶栓治疗,rt-PA组急性缺血性脑卒中患者在常规治疗基础上加用重组组织型纤溶酶原激活剂(rt-PA)静脉溶栓治疗。结果:治疗2周后,rt-PA组、尿激酶组急性缺血性脑卒中患者总有效率均明显高于对照组(P<0.05),rt-PA组、尿激酶组急性缺血性脑卒中患者总有效率比较差异无统计学意义(P>0.05)。结论:早期进行溶栓治疗可有效改善急性缺血性脑卒中患者的临床疗效、生活能力与神经功能。Objective：To explore the clinical effect of thrombolytic therapy for acute ischemic stroke.Methods：124 patients with acute ischemic stroke were selected,they were divided into the control group,the urokinase group and the rt-PA group.The control group was treated with routine treatment,the urokinase group was treated with urokinase thrombolytic therapy on the basis of routine treatment,the rt-PA group was treated with recombinant tissue plasminogen activator（rt-PA） intravenous thrombolytic therapy on the basis of conventional therapy.Results：After 2 weeks of treatment,the total effective rate of the rt-PA group and the urokinase group was significantly higher than that of the control group（P〈0.05）,there was no significant difference in the total effective rate between the rt-PA group and the urokinase group（P〈0.05）.Conclusion：Early thrombolytic therapy can effectively improve the clinical efficacy,viability and neurological function of patients with acute ischemic stroke.

关 键 词：急性缺血性脑卒中 静脉溶栓 尿激酶 重组组织型纤溶酶原激活物 临床疗效 

分 类 号：R743.3[医药卫生—神经病学与精神病学]