蒙特利尔认知评估量表在筛查COPD患者轻度认知功能障碍的价值  

Value of Montreal cognitive assessment scale in diagnosing mild cognitive impairment in patients with chronic obstructive pulmonary disease

作　　者：郁芳芳 王兰[1] 刘澄英[1] 江莲[1] 唐良法[1] YU Fang-fang;PANG Lan;LIU Cheng-ying;JIANG Lian;TANG Liang-fa(Department of Respiration Medicine,Jiangyin People＇s Hospital Affiliated to Southeastern University,Jiangyin,Jiangsu 214400,China)

机构地区：[1]东南大学医学院附属江阴市人民医院呼吸内科,江苏江阴214400

出　　处：《临床肺科杂志》2018年第11期2045-2047,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的对慢性阻塞性肺疾病(COPD)患者应用蒙特利尔认知评估量表进行筛查,对其应用于轻度认知功能障碍识别的临床价值进行分析,并讨论慢性阻塞性肺疾病患者认知功能障碍的神经心理学特点。方法将符合纳入标准的300例COPD患者作为受试者,依次运用简明精神状态量表(MMSE)、蒙特利尔认知评估量表(MoCA)对患者进行相关的认知功能测定,记录这两个量表对应的认知领域得分,评估两种认知筛查测试的有效性。结果以26分为分界值,蒙特利尔认知评估量表评分显著低于简明精神状态量表且具有统计学差异(P <0. 01),两者在总评分上亦具相关性(r=0. 89,P <0. 05)。简明精神状态量表筛查MCI的敏感度为55. 3%,特异度为86. 1%;蒙特利尔认知评估量表则分别为96. 3%与78%(P <0. 01),在简明精神状态量表评定为正常认知能力者尚有171例在蒙特利尔认知评估量表中认定为存在轻度认知功能障碍。结论MoCA较MMSE能更有效的筛查到COPD患者早期发生的认知损害。Objective To assess the clinical value of Montreal cognitive assessment seal （MoCA） in reeognitioin of mild cognitive impairment （ MCI）, and to discuss the neuropsyehological characteristics of padents with chronic obstructive pulmonary disease （COPD）. Methods Totally 300 consecutive patients with COPD were enrolled in our study. Participants underwent a comprehensive cognitive assessment using Mini-mental State Examination scale （MMSE） and Montreal cognitive assessment scale （ MoCA ）. Tire cognitive domains scores of tire two scales were recorded, and the effectiveness and validity of the two cognitive screening tests were assessed. Results With a cut-off score of 26, the score of the Montreal cognitive assessment scale was obviously lower than Mini-mental state examination （P 〈 0. 01）. Pearson correlation analysis showed that MoCA and MMSE were highly correlated （ r =0. 89, P 〈0. 05）. Tire sensitivity of MoCA was 96.3% , and tire specificity was 78% , and MMSE were 55.3% and 86. 1% ,respectively （P 〈0. 01 ）. 171 patients had been assessed as normal cognitive abilities in MMSE, which were identified as mild cognitive impairment using MoCA. Conclusion MoCA is more effective than MMSE in screening early cognitive impairment in patients with COPD.

关 键 词：慢性阻塞性肺疾病 轻度认知障碍 蒙特利尔认知评估量表 

分 类 号：R749.1[医药卫生—神经病学与精神病学] R563.9[医药卫生—临床医学]