罕见鼻部皮肤肌纤维瘤1例（英文）  

A rare case report for dermatomyofibroma in nasion

作　　者：付思祺[1] 张静[1] 湛意[1] 张慧明[1] Edward I.Herman 陆前进[1] 周英[1] 张桂英[1] FU Siqi1, ZHANG Jing1, ZHAN Yi1, ZHANG Huiming1, Edward I. Herman2, LU Qanjin1, ZHOU Ying1, ZHANG Guiying1(1. Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha 410011, China; 2. St. Vincent＇s Medical Center, Bridgeport CT 06606, US)

机构地区：[1]中南大学湘雅二医院皮肤科,长沙410011 [2]圣文森特医学中心,美国康乃狄克州布里奇波特06606

出　　处：《中南大学学报（医学版）》2018年第9期1037-1040,共4页Journal of Central South University ：Medical Science

基　　金：This workwas supported by the Natural Science Foundation of Hunan Province, China (2018JJ3756).

摘　　要：皮肤肌纤维瘤是一种少见的良性皮肤软组织肿瘤,病变为成纤维细胞和肌成纤维细胞增殖,常见于年轻成年人和青少年的肩部及颈部,其次好发于上臂、大腿、胸壁、背部、腋窝和腹部。本文报道1例罕见发生于鼻部的皮肤肌纤维瘤,此例肿物表现为无症状的坚硬的皮肤结节,病理上证实与皮肤肌纤维瘤相符。免疫组织化学结果显示,肿瘤细胞表达波形蛋白(vimentin)、肌特异性肌动蛋白(HHF35)和平滑肌肌动蛋白(α-smooth muscle actin,α-SMA)。手术切除后随访2年无复发。Dermatomyofi broma is a benign and rare proliferation of myofi broblasts and fi broblasts of the skin. Dermatomyofi broma commonly locates at the shoulder and neck of young adults and adolescents. Other frequently affected anatomic sites are upper arms, thigh, chest wall, back, axillary region and abdomen. Herein, we reported a case of dermatomyofibroma occurred in the nasion. The asymptomatic fi rm nodule and histopathological features were consistent with dermatomyofi broma. Immunohistochemically, the tumor cells expressed vimentin, HHF35 and α-smooth muscle actin （α-SMA）. Th e patient was followed up for 2 years aft er excision of the tumors and recurrences were not observed.

关 键 词：皮肤肌纤维瘤 鼻部 肌纤维母细胞瘤 

分 类 号：R739.5[医药卫生—肿瘤]