NAFLD患者MR IDEAL-IQ序列下FF与TBF、BMI的相关性  

Correlation between liver fat content and body fat and BMI of nonalcoholic fatty liver disease under MR IDEAL-IQ sequence

作　　者：吴李贤[1] 刘全妹[1] 陈永凤[1] 袁文春 WU Li-xian;LIU Quan-mei;CHEN Yong-feng;YUAN Wen-chun(Department of lnfectious,the First People＇s Hospital of Foshan,Foshan,Guangdong 528000,China)

机构地区：[1]佛山市第一人民医院感染科,广东佛山528000

出　　处：《热带医学杂志》2018年第9期1163-1166,1217,共5页Journal of Tropical Medicine

摘　　要：目的研究非酒精性脂肪肝(NAFLD)患者MR IDEAL-IQ序列下肝脏脂肪含量脂肪分数(FF)与体内脂肪百分比(TBF)、体质量指数(BMI)的相关性。方法纳入86例NAFLD患者为A组,另选取同期健康体检者50人为B组,纳入对象均接受双能X线吸收骨密度仪测定TBF及局部体脂参数(躯干、上肢、下肢),并记录BMI值,另接受MR IDEAL-IQ序列,得出FF值,比较A、B组及不同程度(轻、中、重)NAFLD患者BMI、体脂相关参数、FF值差异,线性相关分析FF值与体脂、BMI的相关性,并将以上指标纳入自变量非条件Logisistic多因素回归分析与NAFLD发病的关系。结果 A组BMI、TBF、躯干体脂、上肢体脂、下肢体脂及FF值较B组明显升高,差异有统计学意义(P<0.05);随病情程度加重,BMI、TBF、躯干体脂占比、上肢体脂占比、下肢体脂占比及FF呈显著增加趋势(P<0.05);FF与TBF、BMI均呈显著正相关(R^2=0.900、0.590);FF值是NAFLD的独立危险因素(P<0.05)。结论 MR Ideal-IQ序列下FF与TBF、BMI有良好的相关性,需引起临床重视。Objective To study the correlation of liver fat content and fat fraction （ FF ） with body fat percentage （TBF） and body mass index （BMI） with nonalcoholic fatty liver disease （NAFLD） by MR and IDEAL-IQ sequences. Methods 86 patients with NAFLD were enrolled in the A group, and 50 healthy subjects in the same period were selected as the B group. Participants underwent dual energy measurement of whole body fat content and body fat parameters of local X-ray absorptiometry （trunk, upper and lower limbs）, and recorded for the BMI value, the MR IDEAL-IQ sequences and the FF value. The differences of BMI, body fat related parameters and FF value in patients with A, B group and different degree （B Ultrasound divided into mild, medium and heavy） NAFLD were analyzed by linear correlation analysis, and the correlation between FF value and body fat, BMI was analyzed. The above indexes were included in the independent variables, non conditional logistic regression analysis and the analysis of relationship between NAFLD and nonalcoholic fatty liver disease. Results The BMI, TBF, trunk body fat, upper limb fat, lower limb body fat and FF of group A were significantly higher than those of group B （P〈O.05）. BMI, TBF and trunk body fat were aggravated with the severity of the disease. The proportion of body fat, upper body fat percentage, lower limb body fat percentage and FF increased significantly （P〈0.05） ; liver fat content was significantly positively correlated with TBF and BMI, R2=0.900, 0.590; FF value was non-alcoholic Independent risk factors for fatty liver （P〈O.05）. Conclusion MR Ideal-IQ liver fat content measurement FF has a good correlation with body fat and BMI, which needs clinical attention.

关 键 词：MR Ideal-IQ序列 肝脏脂肪含量 体内脂肪百分比 BMI 

分 类 号：R575.5[医药卫生—消化系统]