中下段食管癌适形联合调强放疗对心肺组织的影响  

Effect of conformal radiotherapy combined with intensity-modulated radiation therapy on heart and lung tissue in patients with middle and lower esophagealcarcinoma

作　　者：玉贵永 邹良群[1] 罗剑锋[1] 冯凯华[1] YU Guiyong, ZOU Liangqun, LUO Jianfeng, et al(Department of Radiotherapy, the First Aff＇fliated Hospital of Guilin Medical University, Guilin 541001, China)

机构地区：[1]桂林医学院附属医院,广西桂林541001

出　　处：《华夏医学》2018年第5期41-44,共4页Acta Medicinae Sinica

摘　　要：目的:探讨中下段食管癌适形联合调强放疗对心肺组织的影响。方法:将中下段食管癌患者40例,随机分为A、B两组,A组采用适形联合调强放疗(包括适形放疗10次,调强放疗20次)。B组采用单纯适形放疗30次。分析两组心、肺及左右冠状动脉接受的照射剂量。结果:A组患者心脏、右冠状动脉、左冠状动脉及双侧肺接受的放射量均明显低于B组,差异有统计学意义(P<0.05)。结论:适形联合调强放疗能降低患者心、肺的放射照射量,减轻心肺等器官的损害。Objective： To investigate the effect of conformal radiotherapy combined with intensity-modulated radiation therapy on heart and lung tissue in patients with middle and lower esophageal carcinoma.Methods： 40 patients with middle and lower esophageal cancer were randomly divided into two groups： A and B. A was treated with conformal radiotherapy combined with intensity-modulated radiation therapy（ including conformal radiotherapy 10 times,intensity modulated radiotherapy 20 times）. Group B was treated with simple conformal radiotherapy for 30 times. The radiation dose of heart,lung and left and right coronary arteries of two groups was analyzed. Results： The radiation dose of heart, right coronary artery,left coronary artery and bilateral lung in group A was significantly lower than that in group B（ P〈0.05）. Conclusion： Conformal combined intensity modulated radiation therapy can reduce the radiation dose of heart and lung and reduce the damage of organs such as heart and lung.

关 键 词：食管癌 3维适形放疗 调强放疗 心肺损伤 

分 类 号：R735.1[医药卫生—肿瘤] R818.74[医药卫生—临床医学]