益生元对肥胖相关肠道微生态的影响  

The impact of prebiotics on intestine microecology related to obesity

作　　者：张蓉 费宇行[2] 曾强[1] ZHANG Rong;FEI Yuxing;ZENG Qiang(Health Management Institute,Chinese PLA General Hospital,Beijing 100853,China;Department of Cardiology,Navy General Hospital,Beijing 100048,China)

机构地区：[1]解放军总医院健康管理研究院,北京100853 [2]海军总医院心脏中心,北京100048

出　　处：《转化医学杂志》2018年第5期309-313,共5页Translational Medicine Journal

摘　　要：近年,肥胖发病率显著增加,成年期慢性病及代谢综合征随之增加,据统计每年有2 800万人死于超重或肥胖的并发症。肠道微生态与人体健康和疾病的关系逐渐被揭示,肠道菌群紊乱可能是导致肥胖及相关代谢紊乱的原因。益生元能够为肠道益生菌发酵利用,增加原籍益生菌、遏制有害菌,减低机体炎症状态,改善糖脂代谢,调节肠道激素变化,从而改善肥胖及肥胖相关代谢紊乱。In recent decades, rates of obesity have increased significantly, resulting in the development of chronic diseases and metabolic syndrome. Each year, 28 million individuals are dying from the consequences of overweight or obesity worldwide according to figures. In recent years, intestine mieroeeology in the relationship between human health and obesity has been revealed, gut mierobiota may be the cause of obesity and obesity-related metabolic disorders. Prebioties can be fermented by mieroflora, it can increase intestinal origin probioties, inhibit harmful bacteria and inflammation, improve the glucose and lipid metabolism, regulate gut hormone secretion and improve obesity related metabolic disorders.

关 键 词：益生元 肥胖 肠道微生态 

分 类 号：R589.2[医药卫生—内分泌]