非酒精性脂肪性肝病患者并发膝关节骨性关节炎时健步走方案研究  

Study of Walking Program on Nonalcoholic Fatty Liver Disease Patients with Knee Osteoarthritis

作　　者：张猛[1] 孙莉 冯麟[1] Zhang Meng;Sun Li;Feng Lin(Sport Hospital Attached to CDSU,Chengdu,Sichuan 610041,China)

机构地区：[1]成都体育学院附属医院骨科,四川成都610041

出　　处：《四川医学》2018年第9期973-977,共5页Sichuan Medical Journal

基　　金：国家科技支撑计划项目(编号:2012BAK21B01)

摘　　要：目的观察NAFLD并发膝OA患者分段健步走方案疗效是否能达到临床治疗标准。方法将132例NAFLD患者按照膝关节Lysholm评分分为A组(Lysholm评分≥85分,膝关节功能良好)、B组(Lysholm评分65～84分,膝关节功能尚可)、C组(Lysholm评分≤65分,膝关节功能较差),分别实施不同的健步走方案进行干预。试验前后分别检测身体形态(体质量、BMI)、膝关节Lysholm评分、肝脏B超影像学指标和血液生化指标(TC、TG、LDL)。结果 (1)三组受试者的体质量、BMI较干预前均有显著下降,差异有统计学意义(P<0. 01);干预后三组的体质量、BMI相比差异无统计学意义(P>0. 05)。(2)干预后B、C组的膝关节Lysholm评分较干预前均有显著提高,差异有统计学意义(P<0. 01)。(3)肝脏B超影像学指标显示,肝组织表面脂肪覆盖率干预后三组较干预前均有显著下降,差异有统计学意义(P<0. 05),干预后组间比较差异无统计学意义(P>0. 05)。(4)4血液生化指标(TC、TG、LDL)干预后三组较干预前均显著下降,差异有统计学意义(P<0. 05)。结论 NAFLD患者并发膝OA的患者采用经过调整后的健步走方案进行运动锻炼,可以达到与膝关节功能正常的NAFLD患者相同的疗效,同样可以有效控制NAFLD。Objective To observe wether the effect of walking program on NAFLD patients with OA can reach the clinical therapic standard. Methods According to Lysholm Scoring System,132 NAFLD patients with OA were divided into Group A（ Lysholm Score≥85,with good knee function）,Group B（ Lysholm Score in 65～84,with fair knee function）,Group C（ Lysholm Score≤65,with bad knee function）,and different types of walking programs were implemented as intervention. Body morphology（ body mass and BMI）,knee Lysholm Score,liver B-ultrasonic image,blood biochemical indices（ TC,TG,LDL） were deceted before and after the experiment. Results 1 The body mass and BMI of the three groups were significantly decreased compared with that before the intervention,and the difference was statistically significant（ P〈0. 01）; there was no statistically significant difference in body mass and BMI between the three groups after intervention（ P〉0. 05）; 2 after intervention,the knee Lysholm Score of group B and group C was significantly higher than that before intervention,and the difference was statistically significant（ P〈 0. 01）; 3 the liver B-ultrasound imaging showed that the fat coverage on the surface of liver tissue decreased significantly in all three groups after intervention compared with that before intervention,and the difference was statistically significant（ P 〈 0. 05）,while there was no significant difference among the groups after intervention（ P〉0. 05）; 4 blood biochemical indexes（ TC,TG,LDL） were significantly lower in the three groups after the intervention than before the intervention,and the difference was statistically significant（ P 〈0. 05）. Conclusion NAFLD Patients complicated with knee OA are able to achieve the same therapic effect as those with NAFLD with normal knee function by using an adjusted walking program,and it can also effectively prevent the aggravation of NAFLD.

关 键 词：非酒精性脂肪肝 膝关节骨性关节炎 健步走方案 

分 类 号：R575.5[医药卫生—消化系统] R455[医药卫生—内科学]