不同植骨材料在良性骨肿瘤患者植骨重建的疗效  

Comparison of the effect of different bone graft materials in the reconstruction of bone graft in patients with benign bone tumor

作　　者：马中瑞 王文己[2] MA Zhongrui;WANG Wenji(Department of Orthopedics,Minqin People＇s Hospital,Wuwei 733399,China;Department of Orthopedics,the First Hospital Affiliated to Lanzhou University,Lanzhou 730000,China)

机构地区：[1]民勤县人民医院骨科,甘肃武威733399 [2]兰州大学第一医院骨科,甘肃兰州730000

出　　处：《中国肿瘤外科杂志》2018年第5期323-326,共4页Chinese Journal of Surgical Oncology

摘　　要：目的探讨不同植骨材料在良性骨肿瘤患者术后植骨重建的疗效。方法分析2011年1月至2016年1月甘肃武威民勤县人民医院收治的120例良性骨肿瘤患者,根据植骨重建术使用的植骨材料分为异体骨组,羟基磷灰石组、硫酸钙组,每组各40例。比较3组患者植骨后愈合速度、愈合率、经济成本。随访2~5年,分析患者的预后情况。结果异体骨组、羟基磷灰石组、硫酸钙组术后12个月愈合率分别为97.5%、92.5%、87.5%,差异无统计学意义(P>0.05)。异体骨组初步愈合时间短于羟基磷灰石组和硫酸钙组(P<0.05),羟基磷灰石组和硫酸钙组相比差异无统计学意义(P>0.05)。术后18个月,异体骨组、羟基磷灰石组、硫酸钙组肢体功能优良率分别为92.5%、85.0%、82.5%,差异无统计学意义(P>0.05)。3组术后KPS评分均明显升高(P<0.05),异体骨组术后6个月、12个月KPS评分均高于羟基磷灰石组和硫酸钙组(P<0.05),术后3个月及术后18个月3组KPS评分差异无统计学意义(P>0.05)。异体骨组治疗费用0.95~1.53(1.21±0.57)万元;羟基磷灰石组治疗费用0.93~1.36(1.18±0.34)万元,硫酸钙组治疗费用0.84~1.17 (1.03±0.34)万元;3组费用比较差异无统计学意义(P>0.05)。结论硫酸钙和羟基磷灰石人工骨植入骨愈合率与异体骨植入相似。Objective To investigate the effects of different bone graft materials on the reconstruction of bone graft in patients with benign bone tumor.Methods From January 2011 to January 2016,120 patients with benign bone tumor were treated in our hospital,considered as the research object.According to the difference of the bone graft materials,120 cases were divided into the allogeneic bone group（n = 40）,the hydroxyapatite group（n = 40） and the calcium sulfate group.The healing speed,healing rate and economic cost after bone graft operation in three groups were compared.Followed-up for 2-5 years,the prognosis of three groups was analyzed.Results The healing rates of the allogeneic bone group,the hydroxyapatite group and the calcium sulfate group were 97.5%,92.5% and 87.5%,respectively.There was no significant difference between three groups（P〉 0.05）.The initial healing time of the allogeneic bone group was significantly shorter than that of the calcium sulfate group and the hydroxyapatite group（P〈 0.05）,but there was no significant difference between the calcium sulfate group and the hydroxyapatite group（P 〉 0.05）.After operation 18 months,the excellent and good rates of limb function in the allogeneic bone group,the hydroxyapatite group and the calcium sulfate group were 92.5%,85.0% and 82.5%,respectively.The difference was not statistically significant（P〉0.05）.The scores of KPS in the three groups were significantly increased（P〈0.05）.The 6-month and 12-month KPS scores of the allogeneic bone group were higher than those of the hydroxyapatite group and the calcium sulfate group（P〈0.05）.The 3-month and 18-month postoperative KPS scores among the three groups were not statistically significant（P〉0.05）.The total cost in the allogeneic bone group was 9,500-15,300 RMB,with an average of（12,100±5,700） RMB.The treatment cost in the calcium sulfate group was 8,400-11700 RMB（average of 10,300± 3,400 RMB）,and the hydroxyapatite group was 9,300 - 13,600 RMB[average of�

关 键 词：骨肿瘤 良性瘤 骨移植 异体骨 人工骨 植骨重建 

分 类 号：R738[医药卫生—肿瘤]