响应面法优化桦菌芝多糖的超声辅助提取工艺  

Optimization in Ultrasonic-Assisted Extraction Process of PhropolyporusfomentariusPolysaccharides by Response Surface Methodology

作　　者：陈胜发[1] 彭修娟[2] 顾国强 刘学红 许海燕[2] CHEN Sheng-fa;PENG Xiu-juan;GU Guo-qiang;LIU Xue-hong;XU Hai-yan(Yangling Vocational Technology College,Yangling 712100,China;Shaanxi Institute of InternationalTrade ＆ Commerce,Xianyang 712046,China;Shandong Buchang Pharmaceuticals Co.,Ltd.,Heze 274000,China;Shaanxi University of Traditional Chinese Medicine,Xianyang 712046,China)

机构地区：[1]杨凌职业技术学院,陕西杨凌712100 [2]陕西国际商贸学院,陕西咸阳712046 [3]山东步长制药有限公司,山东菏泽274000 [4]陕西中医药大学,陕西咸阳712046

出　　处：《化学与生物工程》2018年第10期31-35,共5页Chemistry & Bioengineering

基　　金：陕西省大学生创新训练项目(1953);咸阳市科技局重大专项(2014k01-21)

摘　　要：以桦菌芝多糖提取率为指标,在单因素实验的基础上,采用响应面法优化桦菌芝多糖的超声辅助提取工艺。确定最佳提取条件为:超声温度60℃、超声时间20min、料液比1∶25(g∶mL)、超声频率80kHz,在此条件下,桦菌芝多糖提取率可达2.25%。Using the extraction rate of Phropolyporus fomentarius polysaccharides as an evaluation index,we optimized the ultrasonic-assisted extraction process of Phropolyporus fomentarius polysaccharides by response surface methodologies on the basis of single-factor experiments.The optimum extraction conditions can be determined as follows：the ultrasonic temperature of 60 ℃,the ultrasonic time of 20 min,the solid-liquid ratio of 1∶25（g∶mL）,and the ultrasonic frequency of 80 kHz.Under above conditions,the extraction rate of Phropolyporus fomentarius polysaccharides reaches 2.25%.

关 键 词：桦菌芝多糖 超声辅助提取 响应面法 

分 类 号：R284.2[医药卫生—中药学]