纳曲酮口服防复吸治疗回顾性分析  

Retrospective analysis of oral anti-aspiration treatment with naltrexone

作　　者：张薇 徐浩博 ZHANG Wei;XU Hao-bo(Shanxi 109 Hospital,Taiyuan City 030006)

机构地区：[1]山西省一0九医院,太原市030006

出　　处：《中国药物滥用防治杂志》2018年第5期263-265,共3页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:探讨患者纳曲酮防复吸治疗后效果、依从性、疗程和复吸率。方法:采用回顾性研究,通过筛查2013年1月到2015年1月在我院药物依赖科住院的1832例阿片样物质依赖综合征诊断患者,并经过脱毒治疗成功,自愿接受纳曲酮片口服治疗的患者56例,所有被试者经过电话、来院回访、定期尿检超过2年,收集到56例患者资料进行统计分析。结果:56例研究对象中大部分均有固定职业及收入,家庭支持系统较好,44例患者服药2年以上,随访期内未发现复吸情况。结论:有固定职业及收入、家庭支持系统较好且纳曲酮服药时间较长可能是确保纳曲酮防复吸治疗效果的有利因素。Objective： To explore the effect, compliance, course of treatment and relapse rate after treatment with naltrexone. Methods： Using retrospective studies, Screening of 1832 patients with opioid dependence syndrome who were hospitalized in our hospital from January 2013 to January 2015, and successfully treated with detoxification. 56 patients who voluntarily received naltrexone tablets for oral treatment. All subjects received telephone calls, visits to the hospital and regular urine tests for more than 2 years. Data of 56 patients were collected for statistical analysis. Results： Most of the 56 cases had fixed occupation and income, better family support system. 44 patients took medicine for more than 2 years, and no relapse occurred during the follow-up period. Conclusion： Fixed occupation and income, better family support system and longer duration of naltrexone administration may be favorable factors to ensure the efficacy of naltrexone treatment.

关 键 词：纳曲酮片 防复吸 阿片样物质依赖 

分 类 号：R749.6[医药卫生—神经病学与精神病学]