血细胞分析仪散点图及报警信息在恶性血液病诊断中的意义  

Significance of hematology analyzer scatter chart and alarm information in the diagnosis of hematological malignancies

作　　者：张娜[1] 任方刚[2] 郭存九[1] Zhang Na;Ren Fanggang;Guo Cunjiu(Department of Laboratory,the Second Hospital of Shanxi Medical University,Taiyuan 030001,China;Department of Hematology Laboratory,the Second Hospital of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]山西医科大学第二医院检验科,太原030001 [2]山西医科大学第二医院血液科实验室,太原030001

出　　处：《白血病．淋巴瘤》2018年第9期517-520,共4页Journal of Leukemia & Lymphoma

摘　　要：目的探讨血细胞分析仪在恶性血液病初步诊断中的作用。方法采用SYSMEX XE-2100血细胞分析仪的血细胞分类计数（DIFF）散点图和报警信息，对山西医科大学第二医院2016年10月至2017年2月收治的121例初发恶性血液病住院患者的血常规结果进行分析。结果121例恶性血液病患者中，96例（79.3%）出现DIFF散点图异常。急性淋巴细胞白血病、慢性淋巴细胞白血病、急性早幼粒细胞白血病、慢性粒细胞白血病患者的DIFF散点图具有各自明显的特点，其他疾病类型的DIFF散点图特征不明显。经血涂片证实，血细胞分析中警示有原始细胞者符合率为87.7%（50/57），有未成熟粒细胞者符合率为76.3%（42/55），有有核红细胞者符合率为33.3%（19/57），有异型淋巴细胞者符合率为43.1%（31/72）。结论血细胞分析仪DIFF散点图及报警信息在恶性血液病诊断中具有重要作用。ObjectiveTo study the role of hematology analyzer in the preliminary diagnosis of hematological malignancies.MethodsThe blood routine results of 121 patients with initial hematological malignancies in the Second Hospital of Shanxi Medical University from October 2016 to February 2017 were analyzed by differential blood count （DIFF） scatter chart and alarm information of hematology analyzer SYSMEX XE-2100.ResultsAmong 121 patients with hematological malignancies, 96 cases （79.3%） had abnormality of DIFF scatter chart. The DIFF scatter chart of acute lymphoblastic leukemia, chronic lymphocytic leukemia, acute promyelocytic leukemia, and chronic myeloid leukemia had their own distinct characteristics, but the features of other types were not obvious. According to blood smear, blood cells analysis alarmed that the coincidence rates of primitive cells, immature granulocytes, nucleated erythroblasts and atypical lymphocytes were 87.7% （50/57）, 76.3% （42/55）, 33.3% （19/57）, 43.1% （31/72） respectively.ConclusionThe DIFF scatter chart of hematology analyzer and alarm information play very important roles in the diagnosis of hematological malignancies.

关 键 词：血液肿瘤 血细胞计数 散点图 诊断 

分 类 号：R733[医药卫生—肿瘤]