从VitaminD-FGF23-Klotho轴角度关于“心肾相交”理论的现代医学本质探讨  

Discussion on Material Basis of Heart-kidney Intercourse Basedon Vitamin D-FGF23-Klotho Axis

作　　者：陈伟[1] 吴建屏 管连城 王焕珍 高洁[3] 陈云志[3] 柴艺汇 CHEN Wei;WU Jianping;GUAN Liancheng;WANG Huanzhen;GAO Jie;CHEN Yunzhi;CHAI Yihui(Yongjia Branch Hospital of The First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325100,Zhejiang,China;Postgraduate School of Guiyang University of Chinese Medicine,Guiyang 550002,Guizhou,China;Basic Medical School,Guiyang University of Chinese Medicine,Guiyang 550002,Guizhou,China;Experiment Center,Guiyang University of Chinese Medicine,Guiyang 550002,Guizhou,China)

机构地区：[1]温州医科大学附属第一医院永嘉分院,浙江温州325100 [2]贵阳中医学院研究生院,贵州贵阳550002 [3]贵阳中医学院基础医学院,贵州贵阳550002 [4]贵阳中医学院实验中心,贵州贵阳550002

出　　处：《中华中医药学刊》2018年第10期2491-2493,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81660762,81373517);贵州省科技合作计划项目(2015GZ53841);贵州省一流学科建设项目(GNYL2017008)

摘　　要：中医学＂肾＂的现代生物学本质已被证明与维生素D轴存在关系,中医学＂心＂的部分脏腑功能维持及失常被认为与肾素-血管紧张素系统激活有关,通过对最新Vitamin D-FGF23-Klotho轴以及RAS相关的研究进展进行回顾提出中医学＂心肾相交＂理论的物质基础可能与Vitamin D-FGF23-Klotho轴、RAS、维生素D轴功能有关。It has been proved Vitamin D axis has a larger association withkidney of traditional Chinese medicineand theactivation of RAS is regarded as the material basis ofcardiac malfunction. By reviewing the findings of Vitamin D-FGF23-Klotho axis,we conclude that the material basis of theintercourse between heart and kidney is associated with Vitamin D-FGF23-Klotho Axis,RAS Vitamin Daxis.

关 键 词：心肾相交 维生素D轴 VITAMIN D-FGF23-Klotho轴 RAS 

分 类 号：R2-03[医药卫生—中医学]