不同类型静坐不能三例分析  

Different types of akathisia: clinical analysis on three cases

作　　者：王磊[1] 汪明玉 吴金龙 李昀 钟池[1] WANG Lei;WANG Ming-yu;WU Jin-long;LI Yun;ZHONG Chi(Department of Neurology,Weifang People＇s Hospital,Weifang 261000,Shandong,China;Department of Neurology,Yidu Central Hospital,Weifang 262500,Shandong,China)

机构地区：[1]山东省潍坊市人民医院神经内科,261000 [2]山东省潍坊市益都中心医院神经内科,262500

出　　处：《中国现代神经疾病杂志》2018年第9期688-691,共4页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：山东省医药卫生科技发展计划项目(项目编号:2014WS0266)~~

摘　　要：目的探讨不同类型静坐不能的临床表现、可能发病机制和治疗方法。方法与结果共3例静坐不能患者,例1诊断为急性静坐不能、药源性帕金森综合征、缺铁性贫血,停用奥氮平,予普萘洛尔、阿普唑仑、苯海索和补铁治疗后好转;例2诊断为迟发性静坐不能、迟发性运动障碍,逐渐减停利培酮、加用阿普唑仑后好转;例3诊断为帕金森病静坐不能,继续予抗帕金森病药多巴丝肼、司来吉兰、普拉克索,加用阿普唑仑、普萘洛尔后好转。结论不同类型静坐不能的治疗方法各异,临床应根据不同类型进行针对性治疗。Objective To explore the clinical presentations,probable pathogenesis and therapy of different types of akathisia.Methods and ResultsThere were 3 cases of akathisia in this report.The diagnosis of Case 1 was acute akathisia,drug-induced parkinsonism,and iron-deficiency anemia,and the symptoms were relieved after the patient stopped taking olanzapine and was treated with propranolol,alprazolam,benzhexol and iron supplementation.The diagnosis of Case 2 was tardive akathisia and tardive dyskinesia.After risperidone was gradually reduced and alprazolam was added,the symptoms were improved.The diagnosis of Case 3 was akathisia in Parkinson’s disease（PD）.After alprazolam and propranolol were added,while anti-PD drugs（levodopa and benserazide,selegiline and pramipexole）continued to be applied,the symptoms were alleviated.ConclusionsWhen akathisia is treated,its type should be distinguished firstly,and then the treatment should be given according to different types.

关 键 词：精神运动性激动 抗精神病药 

分 类 号：R749[医药卫生—神经病学与精神病学]