某院121例脑卒中合并非瓣膜性房颤患者的用药现状分析  

Analysis of Drug Application Status in the 121 Stroke Merge Nonvalvular Atrial Fibrillation with a Hospital

作　　者：田霞[1] 崔颖[1] TIAN Xia ＊;CUI Ying(Affiliated Tianyou Hospital of Wuhan University of Science and Technology-,Wuhan 430064,China)

机构地区：[1]武汉科技大学附属天佑医院,湖北武汉430064

出　　处：《现代医院》2018年第9期1371-1373,共3页Modern Hospitals

摘　　要：目的分析某院脑卒中合并非瓣膜性房颤(Nonvalular Atrial Fibrillation,NVAF)患者抗凝药物应用现状,为临床合理使用抗凝药物提供依据。方法选取2015年1月—2017年12月诊断为NVAF的住院患者共121例,进行血栓栓塞风险评分、出血风险评分,监测患者PT、APTT、TT、INR和不良事件,对其抗凝药物应用情况进行分析评价。结果 121例患者中有100例CHA2DS2-VASc≥2分,只有7例使用华法林进行抗凝治疗,使用阿司匹林73例,联合使用阿司匹林+氯吡格雷41例,各治疗组凝血功能指标均有不同程度改善,不良事件主要是脑卒中和消化道出血。结论某院NVAF患者抗凝治疗比例较低,与相关指南要求差距较大,应加强和规范该类患者的抗凝治疗。Objective To analysis of drug application status in the 121 stroke merge nonvalvular atrial fibrillation with A hospital and provide the basis for clinical rational use of anticoagulant drugs. Methods A total of 121 patients with strock merge nonvalvular atrial fibrillation from January 2015 to December 2017 were collected. The 121 patients were graded on thrombo -embolism risk score, bleeding risk score and were monitor PT, APTT, TT, INR and adverse event. Results In 121 patients with strock merge nonvalvular atrial fibrillation, 100 patients CHA2DS2 -VASc≥2. 7 patients used warfarin as anticoagulation only, 73 patients used aspirin as anticoagulation, 41 patients used utilization aspirin and clopidogrel. The coagulation function of control was obtained varying degrees improvement in each treatment group, and the adverse event were strocke and gastrointestinal bleeding. Conclusion The ratio of anticoagulation treatment with stroke merge nonvalvular atrial fibrillation of A hospital is lower, and the gap were more with the recommended anticoagulants in guide, the anticoagulation treatment of stroke merge nonvalvular atrial fibrillation patients should standard and enhance.

关 键 词：脑卒中 非瓣膜性房颤 抗凝 华法林 阿司匹林 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R541.75[医药卫生—临床医学]