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作 者:卢红治 王倩[2] 党东 Lu Hongzhi;Wang Qian(Department of Encephalopathy,The First Hospital of Traditional Chinese Medicine in Luoyang(Luoyang 471000)
机构地区:[1]河南省洛阳市第一中医院脑病科,洛阳471000 [2]河南省漯河市中心医院神经内科,漯河462000 [3]陕西省榆林市中医院,榆林719000
出 处:《陕西中医》2018年第11期1524-1526,共3页Shaanxi Journal of Traditional Chinese Medicine
基 金:河南省科技攻关重点项目(092102310181)
摘 要:目的:探讨补肾活血汤对于缺血性脑卒中患者的疗效与神经功能、生活质量与能力的影响。方法:选取缺血性脑卒中患者92例,按照随机数字表法,分为观察组和对照组各46例,两组均给予控制血压、血糖和降颅内压等常规治疗,对照组使用阿司匹林肠溶片进行治疗,观察组患者在此基础上使用补肾活血汤进行联合治疗,观察两组临床疗效、神经功能缺损评分、生活能力、治疗后生活质量评分,对患者凝血功能指标进行比较。结果:观察组总有效率明显高于对照组(P<0.05);治疗前,两组患者神经功能缺损评分和生活能力评分无明显差异(P>0.05);治疗后,观察组神经功能缺损评分降低程度、生活能力评分升高程度更加明显(P<0.05);治疗前,两组患者血小板聚集率、纤维蛋白原、全血黏度、血浆黏度无明显差异(P>0.05);治疗后,两组血液流变学指标均有所改善,且观察组纤维蛋白原、全血黏度降低程度更加明显,差异有统计学意义(P<0.05);观察组患者在生活质量各方面评分均优于对照组(P<0.05)。结论:补肾活血汤可明显提高缺血性脑卒中患者疗效,促进患者神经功能恢复,改善凝血功能。Objective : Explore the effect of Bushen Huoxue decoction on the efficacy and neurological function, quality of life and ability of patients with ischemic stroke. Methods :Choose 92 cases of ischemic cerebral apoplexy patients, according to the stochastic indicator method, randomly divided into observation group and control group, each 46 cases .two groups were given control of blood pressure, blood sugar and lower intracranial pressure, such as conventional treatment, the control group using aspirin enteric-coated metformin hydrochloride treatment, observation group of patients on the basis of using Bushen Huoxue decoction for combination therapy, comparing two groups of clinical curative effect, and the two set of neural function defect scale and life ability score comparison, observe the quality of life scores after treatment in both groups, compared to blood coagulation function in patients with indexes. Results: The total effective rate of the observation group was 86.96%, the control group was 65.22% ( P 〈0.05). Before treatment, there was no statistically significant difference between the scores of neurological deficits and the life ability score of the two groups ( P 〉0.05). After treatment, the scores of both groups were improved, and the scores of neurological function defects and life ability score increased significantly in the observation group ( P 〈0.05). Before treatment, there was no significant difference in platelet aggregation rate, fibrinogen, whole blood viscosity and plasma viscosity in the two groups ( P 〉0.05). After treatment, both groups of hemorheological indexes improved, and the degree of reduction of fibrinogen and whole blood viscosity was more obvious in the observation group ( P 〈0.05). Observation group of patients in the physiological function, physiological functions, physical pain, general health, vitality, social function, emotional function, mental health scores were better than that in control group ( P 〈0.05). Conclusion :The ef
分 类 号:R743.3[医药卫生—神经病学与精神病学]
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