血清淀粉酶、前白蛋白和白蛋白在氨基酸支持经内镜逆行胰胆管造影治疗急性胰腺炎前后的变化及意义  

Effects and significance of serum amylase,prealbumin and albumin in the treatment of acute pancreatitis in encoscopic retrograde cholangiopancreatography with amino acid support

作　　者：刘钢[1] 胡如进[1] 张丽君 马建赢 LIU Gang;HU Rujin;ZHANG Lijun(Department of Breast and Thyroid Surgery,Eastern Hubei Medical Group,Huangshi Central Hospital Affiliated Hospital of Hubei Polytechnic University,Huangshi 435000,China)

机构地区：[1]鄂东医疗集团黄石市中心医院(湖北理工学院附属医院)乳甲胰腺外科,湖北黄石435000

出　　处：《临床外科杂志》2018年第9期693-695,共3页Journal of Clinical Surgery

基　　金：湖北省科技计划资助项目(鄂科技发计【2012】16号)

摘　　要：目的探讨血清淀粉酶、前白蛋白(prealbumin,PAB)和白蛋白(albumin,ALB)在氨基酸支持治疗经内镜逆行胰胆管造影(encoscopic retrograde cholangiopancreatography,ERCP)急性胰腺炎(acute pancreatitis,AP)前后的变化及意义。方法选取经ERCP术诊治的急性胰腺炎患者100例,随机分为2组,每组50例。对照组给予常规手术治疗,观察组在此基础上给予肠外氨基酸营养支持治疗7天,于术前2 h,术后2 h、1 d、2 d和7 d检测患者血清淀粉酶、PAB和ALB水平,同时观察疗效以及患者临床症状缓解情况。结果与对照组相比,观察组患者术后血淀粉酶水平、主要临床症状指标明显缓解,营养状态指标明显上升(P <0. 05)。与对照组相比,观察组治疗总有效率显著升高,差异具有统计学意义(P <0. 05)。结论 ERCP治疗急性胰腺炎给予氨基酸营养支持治疗能有效缓解AP的临床症状,并降低血淀粉酶、PAB和ALB的含量。Objective To investigate the effects and significance of serum amylase,prealbumin（ PAB） and albumin（ ALB） in the treatment of acute pancreatitis（ AP） with amino acid support in ERCP（ encoscopic retrograde cholangiopancreatography）. Methods 100 patients with acute pancreatitis diagnosed by ERCP were randomly divided into two groups（ n = 50）. The control group was given routine surgical treatment. On the basis of this,the treatment group was deal with parenteral amino acid nutrition for 7 days. The serum amylase level was measured at 2 h before operation,2 h,1 d,2 d and 7 d after operation,and the curative and symptom effect were observed. Results Compared with the control group,the serum amylase levels,main clinical symptoms,and nutritional status indicators were significantly relieved in the observation group（ P〈0. 05）. Compared with the control group,the total effective rate of the treatment group was significantly increased,the difference was statistically significant（ P〈0. 05）. Conclusion ERCP treatment of acute pancreatitis to give amino acid nutritional support treatment could effectively relieve the clinical symptoms of AP,and reduce the content of serum amylase.

关 键 词：急性胰腺炎 血淀粉酶 氨基酸支持治疗 内镜逆行胰胆管造影术 前白蛋白 白蛋白 

分 类 号：R576[医药卫生—消化系统]