常规技术和三维放疗技术在食管癌根治性放射治疗中的剂量学对比  

Dosimetric Comparison of Conventional Techniques and Three-dimensional Radiotherapy in Radical Radiotherapy for Esophageal Cancer

作　　者：吕强 吕明明 黄术林 泮卫红[1] 孙成[1] LYU Qiang;LYU Ming-ming;HUANG Shu-lin;PAN Wei-hong;SUN Cheng(Radiotherapy Department,Section One,Zibo Wanjie Cancer Hospital,Zibo,Shandong Province,255203 China)

机构地区：[1]淄博万杰肿瘤医院放疗一科,山东淄博255203

出　　处：《中外医疗》2018年第28期82-84,共3页China & Foreign Medical Treatment

摘　　要：目的探讨食管癌患者在食管癌根治性放射治疗中应用三维放疗技术与常规技术放疗的剂量学对比。方法分析方便选取2015年8月—2017年8月该医院诊治的48例根治性放疗的食管癌患者,30例行三维放疗技术,18例行常规技术放疗。分别对比这48例患者在靶区及危及器官的剂量分布,随后勾画计划靶区,以及周围危及器官,如脊髓、肺、心脏。结果常规技术放疗与三维技术放疗在正常组织保护方面有明显优势,特别是肺、心脏,常规技术放疗中肺V30、脊髓Dmax、心脏V30分别为(10.3±6.7)、(30.2±21.8)、(83.3±14.7),对比三维技术放疗(16.2±7.3)、(42.9±20.5)、(94.3±17.9),差异有统计学意义(t=2.793 4、2.029 4、2.197 6,P=0.007 6、0.048 2、2.197 6)。结论三维技术放疗治疗食管癌患者疗效显著,能够更好的保护患者器官组织。Objective To investigate the dosimetric comparison between three-dimensional radiotherapy and conventional radiotherapy in esophageal cancer patients undergoing radical radiotherapy for esophageal cancer. Methods A total of 48 patients with esophageal cancer who underwent radical radiotherapy from August 2015 to August 2017 were enrolled conveniently. 30 patients underwent three-dimensional radiotherapy and 18 underwent routine radiotherapy. The dose distribution of the 48 patients in the target area and the endangered organs were compared, and then the planned target area and surrounding vital organs such as the spinal cord, lung, and heart were delineated. Results Conventional radiotherapy and three-dimensional radiotherapy have obvious advantages in normal tissue protection, especially in lung and heart. In conventional radiotherapy, lung V30, spinal cord Dmax and heart V30 were （ 10.3 ＋6.7）, （30.2±21.8）, and （83.3 ±14.7 ）, respectively. Three-dimensional radiotherapy was （16.2±7.3）, （42.9±20.5）, and（94.3±17.9）, and the difference was significant （t= 2.793 4, 2.029 4, 2.197 6, P value=0.0076, 0.048 2, 2.197 6）. Conclusion Three-dimensional radiotherapy for patients with esophageal cancer has a significant effect and can better protect the organ tissues of patients.

关 键 词：三维适形放疗 常规技术放疗 食管癌 剂量学研究 

分 类 号：R735.1[医药卫生—肿瘤]