胰十二指肠切除手术治疗胰腺癌的临床分析  

Clinical Analysis of Pancreaticoduodenectomy for Pancreatic Cancer

作　　者：赵应宏 ZHAO Ying-hong(Department of Hepatobiliary Surgery,Pu＇er People＇s Hospital,Pu＇er,Yunnan Province,665000 China)

机构地区：[1]普洱市人民医院肝胆胰外科,云南普洱665000

出　　处：《中外医疗》2018年第27期51-52,58,共3页China & Foreign Medical Treatment

摘　　要：目的分析和探索胰腺癌患者应用胰十二指肠切除手术治疗的效果。方法随机抽取2015年3月—2017年10月该院消化科收治的胰腺癌患者75例,对所有患者进行分组,参照组(n=37)患者应用标准胰十二指肠切除术,探究组(n=38)患者应用扩大胰十二指肠切除术。比较2组患者淋巴结清扫数量、阳性淋巴结清扫数量以及平均手术时间和术中平均出血量、术后并发症情况。结果探究组平均手术时间为(296.4±88.7)min、术中出血量为(799.5±47.3)mL、阳性淋巴结清扫数量为(1.43±0.52)个、淋巴结清扫数量为(11.54±6.20)个,参照组患者分别为(371.7±90.3)min、(796.3±44.1)mL、(1.29±0.42)个、(6.08±1.99)个。探究组患者平均手术时间较参照组患者短,2组差异有统计学意义(t=12.981 2,P=0.020 7),淋巴结清扫数量多于参照组,2组差异有统计学意义(t=9.081 3,P=0.021 9),2组患者术中平均出血量差异无统计学意义(t=0.987 1,P=0.083 4)、2组患者阳性淋巴结清扫数量差异无统计学意义(t=0.836 1,P=0.071 0)。探究组出现并发症患者共计6例,并发症总发生率为15.79%,参照组出血并发症患者共计7例,总发生率为18.92%,2组并发症发生率经对比差异无统计学意义(χ~2=2.184 2,P=0.056 3)。结论胰腺癌患者应用胰十二指肠切除手术治疗有助于缩短患者手术治疗时间,可抑制癌肿转移,对于提升患者的生存质量有重要意义。Objective To analyze and explore the effect of pancreaticoduodenectomy in patients with pancreatic cancer. Methods A total of 75 patients with pancreatic cancer admitted to the hospital from March 2015 to October 2017 were randomly selected. All patients were divided into groups. The control group （n=37） was treated with standard panereatieoduodenectomy. The study group （n=38） underwent extended pancreaticoduodenectomy. The number of lymph node dissection, the number of positive lymph node dissection, the average operation time and the mean intraoperative blood loss, and post-operative complications were compared between the two groups. Results The average operation time of the inquiry group was （296.4±88.7）min, the intraoperative blood loss was （799.5±47.3）mL, the number of positive lymph node disseetion was （1.43±0.52）, and the number of lymph node disseetion was （11.54±6.20）. The patients in the eontrol group were （371.7± 90.3）min, （796.3±44.1）mL, （1.29±0.42）, and （6.08±1.99）, respectively. The average operation time of the patients in the inquiry group was shorter than that of the control group. The difference between the two groups was statistically significant （t= 12.981 2, P=0.020 7）. The number of lymph node dissection was more than that of the reference group. The difference between the two groups was statistically significant （t=9.081 3, P=0.021 9）, the mean bleeding volume difference between the two groups was not significant and not statistically significant （t=0.987 1, P=0.083 4）. There was no significant difference in the number of positive lymph node dissection between the two groups （t=0.836 1, P=0.071 0）. There were 6 patients with complications in the inquiry group, the total incidence of complications was 15.79%, and 7 patients with bleeding complications in the reference group with a total incidence of 18.92%. The incidence of complications in the two groups was not significant and there was no statistical analysis academic signif

关 键 词：胰十二指肠切除手术 胰腺癌 临床疗效 

分 类 号：R735.9[医药卫生—肿瘤]