Peptide aptamer-mediated modulation of prion protein α-cleavage as treatment strategy for prion and other neurodegenerative diseases  

作　　者：Antonia N.Klein Erica Corda Sabine Gilch 

机构地区：[1]Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary [2]Calgary Prion Research Unit, University of Calgary [3]Hotchkiss Brain Institute, University of Calgary

出　　处：《Neural Regeneration Research》2018年第12期2108-2110,共3页中国神经再生研究（英文版）

基　　金：funded by grants from the Alberta Prion Research Institute;the Alzheimer Society of Alberta and Northwest Territories;the Natural Sciences and Engineering Research Council(NSERC)of Canada;supported by the Canada Research Chair program;a postdoctoral fellowship from the German Research Foundation(DFG)

摘　　要：Despite intensive research,most neurodegenerative diseases cannot be cured and for some of them no treatment is available to increase survival or quality of life.Among the latter are prion diseases,fatal and transmissible neurodegenerative diseases of humans and other animals.Despite intensive research,most neurodegenerative diseases cannot be cured and for some of them no treatment is available to increase survival or quality of life.Among the latter are prion diseases,fatal and transmissible neurodegenerative diseases of humans and other animals.

关 键 词：Peptide aptamer-mediated modulation of prion protein cleavage as treatment strategy for prion and other neurodegenerative diseases 

分 类 号：R741[医药卫生—神经病学与精神病学]