顶空固相微萃取-气相色谱-质谱法测定软木塞中愈创木酚的含量  

Determination of Guaiacol in Cork Stopper by GC-MS with Headspace Solid-Phase Microextraction

作　　者：白淼 张灿[1] 甘雨然 张明露[2] 安代志[1] 王强[1] 孙如宝[1] BAI Miao;ZHANG Can;GAN Yuran;ZHANG Minglu;AN Daizhi;WANG Qiang;SUN Rubao(Institute for Disease Prevention and Control of Chinese PLA,Beijing 100071,China;Department of Environmental Science and Engineering,Beijing Technology and Business University,Beijing 100048,China)

机构地区：[1]中国人民解放军疾病预防控制所,北京100071 [2]北京工商大学环境科学与工程系,北京100048

出　　处：《理化检验（化学分册）》2018年第10期1194-1197,共4页Physical Testing and Chemical Analysis(Part B:Chemical Analysis)

摘　　要：取磨碎的软木塞样品0.500 0g,用水超声提取30min,取提取液9mL置于萃取瓶中,加入1.8g Na2SO4,于55℃进行固相微萃取35min后,于气相色谱仪进样口解吸7min,采用气相色谱-质谱法测定其中愈创木酚的含量。结果表明:愈创木酚在25.00～2 000μg·L-1内与其峰面积呈线性关系,检出限(3S/N)为0.022μg·L-1,按标准加入法进行回收试验,回收率为69.8%～115%,测定值的相对标准偏差(n=6)为6.3%～13%。The mashed cork sample （0.500 0 g） was extracted ultrasonically with water for 30 min, and 9 mL of the extract was taken and 1.8 g of Na2 SO4 were added into the extraction bottle. After solid-phase microextraction at 55 ℃ for 35 min, the solution was desorbted for 7 rain at the injection port of the gas chromatography, and guaiacol was determined by GC-MS. As shown by the results, linear relationship between values of peak area and mass concentration of guaiacol was found in the range of 25.00-2 000 μg · L^-1, with detection limit （3S/N） of 0.022 μg · L^-1. Test for recovery was made by standard addition method, giving results in the range of 69.8%- 115%, and RSDs （n=6） ranged from 6.3% to 13%.

关 键 词：气相色谱-质谱法 固相微萃取 愈创木酚 软木塞 

分 类 号：O657.63[理学—分析化学]