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作 者:周群 王毅兴[2] 刘平[1,3] 张华[1] ZHOU Qun;WANG Yixing;LIU Ping(Second Department of Liver Cirrhosis,Shuguang Hospital Affiliated to Shanghai University ofTraditional Chinese Medicin;Institute of Liver Diseases,Shanghai University of Traditional Chinese Medicin;Key Laboratory of Liver andKidney Diseases,Ministry of Educatio;Shanghai Key Laboratory of Traditional Chinese Clinical Medicine,Shanghai 201203,China)
机构地区:[1]上海中医药大学附属曙光医院肝病二科,上海中医药大学肝病研究所,肝肾病证教育部重点实验室,上海市中医临床重点实验室,上海201203 [2]同济大学附属东方医院中医科,上海201200 [3]上海中医药大学上海市高校中医内科学E研究院,上海201203
出 处:《临床肝胆病杂志》2018年第11期2458-2463,共6页Journal of Clinical Hepatology
基 金:国家自然科学基金青年科学基金项目(81603560)
摘 要:胆石症是临床常见、多发病症,目前西医以手术为首要治疗手段,但存在手术创伤、复发率高及术后易发生并发症等问题。中医药治疗胆石症方法多样,疗效满意,近年来在临床上被广为应用。主要从中医对胆石症的认识、中医药治疗方法及其作用机制,以及中西医联合治疗等3个方面对中医药治疗胆石症的研究进展进行归纳总结。认为中医药可明显改善或抑制胆石症的形成,具有疗效可靠、副作用小、复发率低的优势。但目前因存在作用机制不清、临床研究质量不高、可重复性差等缺陷,限制了其进一步推广应用。建议今后进一步加强基础研究及开展高水平的临床随机对照研究,为胆石症的临床诊疗提供更科学、客观的证据,以期提高中医药治疗胆石症的临床疗效。Cholelithiasis is a common disease in clinical practice. At present,surgery is the primary Western treatment method for this disease,but there are problems such as surgical trauma,a high recurrence rate,and postoperative complications. Various traditional Chinesemedicine ( TCM)methods for the treatment of cholelithiasis have achieved satisfactory results and have been widely used in clinical practicein recent years. This article summarizes the research advances in TCM therapy for cholelithiasis from the aspects of the understanding of cholelithiasis in TCM,TCM treatment methods for cholelithiasis and their mechanisms,and integrated traditional Chinese and Western medicinetherapy. It is pointed out that TCM can significantly improve or inhibit the information of cholelithiasis and has the advantages of reliabletherapeutic effect,few side effects,and a low recurrence rate;however,its further application is limited by the unclear mechanism of actionof TCM and defects of related clinical research such as low quality and poor repeatability. It is recommended to strengthen basic research andconduct high - level randomized controlled clinical trials in the future to provide scientific and objective evidence for clinical diagnosis andtreatment of cholelithiasis and thus improve the clinical effect of TCM in the treatment of cholelithiasis.
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