Cumulative probability and risk analysis for Nd:YAG laser capsulotomy  

作　　者：Anna K Junk Evan N Dunn Anat Galor Sarah R Wellik Jesse Pelletier Ninel Gregori William Feuer 

机构地区：[1]Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine [2]Ophthalmology,Miami VAMC [3]Bascom Palmer Eye Institute, University of Miami Miller School of Medicine

出　　处：《World Journal of Ophthalmology》2014年第3期82-86,共5页世界眼科杂志

基　　金：Supported by In part by NEI Core Center,No.P30 EY014801;Research to Prevent Blindness (RPB) Unrestricted Award and Department of Defense;No.#W81XWH-09-1-0675;VA Career Development Award(CDA2) and Stanley Glaser UM to Dr.Anat Galor

摘　　要：AIM: To estimate the cumulative probability of Nd:YAG capsulotomy at a teaching institution and evaluate secondary risk factors.METHODS: The records of all patients who underwent phacoemulsification with intraocular lens(IOL) placement between 2005-2010 were retrospectively reviewed. The cumulative probability of Nd:YAG capsulotomy(capsulotomy) was calculated using KaplanMeier survival analysis and secondary risk factors were evaluated using the Cox proportional hazards regression model. RESULTS: One thousand three hundred and fifty four charts were reviewed. A total of 70 capsulotomies wereperformed. The mean follow-up was 19.4 mo(standard deviation 17 mo). The cumulative probability of capsulotomy was 4% at 1 year, 5% at 2 year, and 9% at 3 year. Multivariate analysis demonstrated an increased risk with younger age(HR = 1.03, CI 1.01-1.05, P = 0.007), placement of sulcus IOL(HR = 2.57, CI 1.32-4.99, P = 0.005), ocular trauma(HR = 2.34, CI 1.13-4.83, P = 0.02), and phacoemulsification by a more experienced surgeon(HR = 4.32, CI 1.89-9.87, P = 0.001).CONCLUSION: Cumulative probability of capsulotomy was lower than previously reported. Posterior capsule opacification was strongly associated with younger age and factors associated with high-risk cataract surgery. Surgeon awareness to the risk factors that correlate with posterior capsulotomy may allow for more thorough pre-operative disclosure and enhance patient satisfaction.AIM： To estimate the cumulative probability of Nd：YAG capsulotomy at a teaching institution and evaluate sec-ondary risk factors.METHODS： The records of all patients who under-went phacoemulsification with intraocular lens （IOL） placement between 2005-2010 were retrospectively reviewed. The cumulative probability of Nd：YAG cap-sulotomy （capsulotomy） was calculated using Kaplan-Meier survival analysis and secondary risk factors were evaluated using the Cox proportional hazards regres-sion model. RESULTS： One thousand three hundred and fifty four charts were reviewed. A total of 70 capsulotomies were performed. The mean follow-up was 19.4 mo （standard deviation 17 mo）. The cumulative probability of capsu-lotomy was 4% at 1 year, 5% at 2 year, and 9% at 3 year. Multivariate analysis demonstrated an increased risk with younger age （HR = 1.03, CI 1.01-1.05, P = 0.007）, placement of sulcus IOL （HR = 2.57, CI 1.32-4.99, P = 0.005）, ocular trauma （HR = 2.34, CI 1.13-4.83, P = 0.02）, and phacoemulsification by a more experienced surgeon （HR = 4.32, CI 1.89-9.87, P = 0.001）.CONCLUSION： Cumulative probability of capsulotomy was lower than previously reported. Posterior capsule opacifcation was strongly associated with younger age and factors associated with high-risk cataract surgery. Surgeon awareness to the risk factors that correlate with posterior capsulotomy may allow for more thor-ough pre-operative disclosure and enhance patient sat-isfaction.

关 键 词：YAG capsulotomy Posterior capsule opacification Cataract surgery Risk factor Surgeon experience Cumulative probability Teaching institution 

分 类 号：R77[医药卫生—眼科]