机构地区:[1]首都儿科研究所流行病学研究室,北京100020 [2]解放军总医院科研处
出 处:《中华预防医学杂志》2018年第11期1130-1135,共6页Chinese Journal of Preventive Medicine
基 金:国家重点研发计划(2016YFCl300100、2016YFc0900602);“十二五”国家科技支撑计戈0(2012BAl03803)
摘 要:目的了解我国7城市6—17岁儿童青少年心血管代谢危险因素的流行状况。方法2013--2015年,采用分层整群抽样方法,在长春、北京、天津、济南、上海、银川、重庆7个城市选择24所学校(包括幼儿园3所,小学、初中和高中各7所),将各年级6-17岁学生全部纳入研究,共纳入12590名研究对象。研究内容包括问卷调查,身高、体重、腰围、血压测量,以及静脉血生化检测(空腹血糖、总胆固醇、甘油三酯及HDL-C)。分别依据国际糖尿病联盟标准2007(IDF2007)、中国儿童青少年代谢综合征定义和防治建议2012(CHN2012)计算代谢综合征(MS)的检出率。结果肥胖、高血压、高血糖和血脂异常检出率分别为12.0%(1497/12491)、18.2%(2193/12035),24.4%(3028/12422)、15.8%(1977/12490)。男生的肥胖、高血压、高血糖及血脂异常检出率均高于女生(P值均〈0.05);应用IDF2007和CHN2012标准,10-17岁儿童青少年MS检出率分别为3.3%(272/8328)、5.4%(453/8325)。随着肥胖类型从非肥胖、单纯一般性肥胖、单纯中心性肥胖到复合型肥胖的变化,高血压、高血糖、高甘油三酯、高总胆固醇、低HDL-C以及血脂异常检出率均呈上升趋势(P值均〈0.001)。结论我国7城市6-17岁儿童青少年心血管代谢危险因素检出率较高,已成为威胁儿童青少年健康成长的重要因素。Objective To describe characteristics of cardiometabolic risk factors of children and adolescents aged 6-17 years in 7 cities in China from 2013 to 2015. Methods Data was from the China Child and Adolescent Cardiovascular Health (CCACH) study. 12 590 children and adolescents were selected from 24 schools (3 kindergartens, 7 primary schools, 7 junior high schools and 7 senior high schools) in seven cities (Changchun, Yinchuan, Beijing, Jinan, Shanghai, Chongqing and Tianjin) during 2013-2015 by using a stratified cluster random sampling method. The demographic characteristics, e.g. birth date, feed status and history of disease, were collected by questionnaires. Anthropometric measurements, i.e. weight, height, waistline, blood pressure, total cholesterol, fasting plasma glucose, triglyceride and high-density lipoprotein, were also collected. The detection rate of metabolic syndrome was calculated respectively according to "international diabetes federation standard " and "definition and prevention of metabolic syndrome in Chinese children and adolescents ". Results The prevalence of cardiometabolic risk factors such as obesity, hypertension, hyperglycemia and dyslipidemia was 12.0%(1 497/12 491), 18.2%(2 193/ 12 035), 24.4%(3 028 / 12 422) and 15.8%(1 977 / 12 490),respectively. The prevalence of these four cardiometabolic risk factors in males was significantly higher than that in females (all P values〈0.05). The prevalence of metabolic syndrome was 3.3%(272/8 328) with international diabetes federation 2007 definition and 5.4% (453/8 325) with Chinese definition among children above 10 years old. The prevalence of hypertension, hyperglycemia, hypertriglyceridemia, high total cholesterol, low high-density lipoprotein-cholesterol and dyslipidemia increased with the change of obesity type from non-obesity to complex obesity (all P values〈O.001). Conclusion The prevalence of cardiometabolic risk factors was still high in children and adolescents, which has bec
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