超声斑点追踪成像技术评价生长激素型垂体瘤患者的左心室收缩功能  

Left Ventricular Systolic Function in Evaluation of Patients with Growth Hormone Type Pituitary Tumor Using Ultrasound Speckle Tracking Imaging

作　　者：黄文燕[1] 何文[1] HUANG Wenyan;HE Wen(Beijing Tian Tan Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京天坛医院,北京100050

出　　处：《中国医学影像学杂志》2018年第11期815-819,823,共6页Chinese Journal of Medical Imaging

摘　　要：目的应用超声斑点追踪成像(STI)分析生长激素(GH)型垂体瘤患者左心室心肌纵向应变及扭转运动参数,评估GH型垂体瘤患者的左心室收缩功能。资料与方法选取2015年10月-2017年11月于北京天坛医院就诊的GH型垂体瘤患者56例,其中GH轻度升高组(GH 8.95～14.80μg/L)41例,GH显著升高组(GH 16.18～86.01μg/L)15例;正常对照组30例。采用STI技术定量分析并比较各组左心室心肌纵向应变及扭转参数。结果 (1)左心室心肌长轴应变:与对照组和GH轻度升高组比较,GH显著升高组左心室心肌各切面的纵向应变和整体纵向应变均较低,差异均有统计学意义(P均<0.01)。(2)左心室心肌扭转:GH轻度升高组患者的左心室扭转角度峰值(15.33±3.17)°明显高于对照组(12.54±2.85)°和GH显著升高组(10.12±2.03)°(P均<0.01),而GH显著升高组左心室扭转角度峰值低于对照组(P<0.01);GH轻度升高组和显著升高组患者的左心室解旋率[分别为(50.0±21.3)%和(45.0±17.7)%]和解旋速度峰值[分别为(-82.89±33.93)°/s和(-80.40±28.54)°/s]低于对照组[(63.0±23.4)%、(-91.22±34.16)°/s],解旋减半时间[分别为(35.27±3.86)ms和(37.55±4.54)ms]较对照组[(31.09±3.23)ms]明显延迟(P均<0.01)。结论 STI技术能够评估GH型垂体瘤患者左心室收缩功能的变化情况。Purpose To analyze the left ventricular myocardial longitudinal strain and twist motion parameters of patients with growth hormone （GH） type pituitary tumor by applying ultrasound speckle tracking imaging （STI）, and to evaluate the left ventricular systolic function in patients with GH type pituitary tumor. Materials and Methods A total of 56 patients with GH type pituitary tumors in Beijing Tiantan Hospital from October 2015 to November 2017 were selected, including 41 cases in mild GH growth group （GH 8.95-14.80 μg/L）, 15 cases in significant GH growth group （GH 16.18-86.01 μg/L）, and 30 cases in normal control group. STI was adopted to quantitatively analyze the left ventricular myocardial longitudinal strain and twist motion parameters, and the results of the three groups were compared. Results （1） Longitudinal strain of left ventricular myocardium： the longitudinal strain and overall longitudinal strain of each section plane of the left ventricular myocardium in the significant GH growth group were all significantly lower than that in the control group and the mild GH growth group, the difference of which was statistically significant （P〈0.01）. （2） Left ventricular myocardial torsion： the peak （15.33±3.17）° of left ventricular torsion angle in the mild GH growth group was significantly higher than that in the control group （12.54±2.85）° and the significant GH growth group （10.12±2.03）° （P〈0.01）, while the peak of left ventricular torsion angle in the significant GH growth group was lower than that in the control group （P〈0.01）. The left ventricular untwisting rate [（50.0±21.3）% and （45.0±17.7）%, respectively] and the peak of untwisting speed [（-82.89±33.93）°/s and （-80.40±28.54）°/s, respectively]in the mild GH growth group and the significant GH growth group were lower than those in the control group [（63.0±23.4）%, （-91.22±34.16）°/s], with HTU [（35.27±3.86） ms and （37.55±4.54） ms, respectivel

关 键 词：垂体肿瘤 生长激素 超声心动描记术 多普勒 彩色 斑点追踪成像 心室功能 左 

分 类 号：R739.41[医药卫生—肿瘤] R730.41[医药卫生—临床医学]