中国儿童青少年血糖分布情况  

Analysis of blood glucose distribution of children and adolescents in China

作　　者：董彦会 王西婕 杨招庚 王政和 李艳辉 高迪[1] 董彬[1] 邹志勇[1] 宋逸[1] 马军[1] DONG Yanhui;WANG Xifie;YANG Zhaogeng;WANG Zhenghe;LI Yanhui;GAO Di;DONG Bin;ZOU Zhiyong;SONG Yi;MA Jun(School of Public Health ＆ Institute of Child and Adolescent Health,Peking University,Beijing 100191,China)

机构地区：[1]北京大学公共卫生学院/北京大学儿童青少年卫生研究所,北京100191

出　　处：《中国学校卫生》2018年第10期1449-1451,共3页Chinese Journal of School Health

基　　金：国家自然科学基金项目(81673192)

摘　　要：目的了解中国儿童青少年空腹血糖水平的分布情况及其随年龄和性别变化趋势,为儿童青少年糖尿病的早期防控提供科学依据。方法采用分层随机整群抽样方法,抽取7个省市(湖南省、宁夏回族自治区、天津市、重庆市、辽宁省、上海市、广东省) 6～18岁儿童青少年共16 745名,进行空腹静脉血血糖测定。结果中国7省市6～18岁儿童青少年空腹血糖平均值为(4.66±0.65) mmol/L,其中男生和女生的空腹血糖平均值分别为(4.73±0.66)和(4.60±0.64) mmol/L,男生高于女生,差异有统计学意义(t=12.88,P<0.05);儿童青少年空腹血糖异常检出率为1.71%(年龄标化检出率为1.83%),男、女生空腹血糖异常检出率分别为2.40%和1.00%(年龄标化检出率分别为2.60%和1.00%),男生高于女生,差异有统计学意义(χ~2=41.98,P<0.05)。男生空腹血糖值和血糖异常检出率均高于同年龄段的女生。男、女生空腹血糖水平和空腹血糖异常检出率的变化趋势基本一致,均随年龄呈双峰或"M"态势。结论中国儿童青少年空腹血糖水平和空腹血糖异常检出率在性别和年龄之间有差别,血糖异常检出率较高,需要引起进一步关注。Objective This study aims to explore the distribution of blood glucose, as well as sex-and age-specific trend in Chinese children and adolescents. Methods A total of 16 745 students aged 6 to 18 were chosen from seven provinces（ Hunan,Ningxia hui autonomous region, Tianjin, Chongqing, Liaoning, Shanghai, Guangdong） in China in 2013 through stratified random cluster sampling. Fasting plasma glucose（ FPG） was evaluated. Results The average level of FPG in children and adolescents aged 6-18 years was 4.66 mmol/L, boys was significantly higher than in girls（ 4.73 mmol/L vs 4.60 mmol/L）（ P〈0.05）. The impaired fasting glucose（ IFG） detection rate was 1.71%（ the age-standardized detection rate was 1.83%）, with boys significantly higher than in girls（ 2.40% vs 1.00%, the age-standardized detection rate was 2.60% and 1.00%, respectively）（ P〈0.05）. Within the same age group, boys had higher FPG and IFG detection rate. The same trends were observed in boys and girls with bimodal or ＂M＂ shape in average level of FPG and IFG detection rate. Conclusion Fasting plasma glucose and impaired fasting glucose prevalence varies in age and sex. High prevalence of IFG in Chinese children and adolescents aged 6-18 years warrants further investigation.

关 键 词：血糖 血液化学分析 糖尿病 青少年 

分 类 号：R179[医药卫生—妇幼卫生保健] R446.1[医药卫生—公共卫生与预防医学]