Adenosine triphosphate maintenance by branched chain amino acids as a novel neuroprotective strategy for retinal neurodegenerative diseases  

作　　者：Tomoko Hasegawa Hanako Ohashi Ikeda 

机构地区：[1]Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine [2]Department of Experimental Therapeutics, Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital

出　　处：《Neural Regeneration Research》2019年第1期82-84,共3页中国神经再生研究（英文版）

基　　金：supported by the Japan Agency for Medical Research and Development(to HOI)

摘　　要：Retinal neuronal cell death is caused in many incurable eye diseases such as retinitis pigmentosa(RP)and glaucoma,which are leading causes of adult blindness.In RP,progressive loss of photoreceptor cells leads to visual disturbance.No established treatments are available to date for this condition,although potential treatments,including regenerative medicine,gene therapy,and neurotropic factor therapy are being investigated.In glaucoma。Retinal neuronal cell death is caused in many incurable eye diseases such as retinitis pigmentosa （RP） and glau- coma, which are leading causes of adult blindness. In RP, progressive loss of photoreceptor cells leads to visual dis- turbance. No established treatments are available to date for this condition, although potential treatments, includ- ing regenerative medicine, gene therapy, and neurotropic factor therapy are being investigated. In glaucoma, retinal ganglion cell death leads to visual disturbance.

关 键 词：眼睛疾病 视网膜 氨基酸 基因治疗 腺苷 分叉 维护 光敏电阻器 

分 类 号：R77[医药卫生—眼科]