耐碳青霉烯类肠杆菌科细菌耐药机制研究进展  

Progress on Mechanism of Carbapenem Antibiotics Resistance of Enterobacteriaceae bacteria

作　　者：叶淑瑶[1] 李怡谰 李凤琴 白瑶 杨保伟[1] Ye Shu-yao;Li Yi-lan;Li Feng-qin;Bai Yao;Yang Bao-wei(College of Food Science and Engineering,Northwest A＆F University,Yangling 712100;Key Laboratory of Food Safety Assessment of Ministry of Health,China National Center for Food Safety Assessment,Beij ing 100021)

机构地区：[1]西北农林科技大学食品科学与工程学院,杨凌712100 [2]国家食品安全风险评估中心卫生部食品安全风险评估重点实验室,北京100022

出　　处：《国外医药（抗生素分册）》2018年第6期494-500,共7页World Notes on Antibiotics

基　　金：国家重点研发计划-食源性微生物耐药参考物质体系研究与评价(2017YFC1601402);国家自然科学基金(No.31671956)

摘　　要：肠杆菌科细菌是导致医院感染和食源性疾病爆发的重要病原菌。随着碳青霉烯类抗生素在世界范围内的大量使用,近年有关肠杆菌科细菌对碳青霉烯类药物耐受的现象屡见不鲜。本文综述了近几年国内外对肠杆菌科细菌碳青霉烯类药物的耐药现状和耐药机制。Enterobacteriaceae bacteria are important pathogens causing nosocomial infections and foodbome outbreaks. With the wide use of carbapenem antibiotics around the world, resistance to carbapenems among Enterobacteriaceae bacteria is gradually acquired as well as corresponding reports about the resistance. In this paper, the progresses on carbapenem resistance and resistance mechanisms of Enterobacteriaceae bacteria were summarized.

关 键 词：碳青霉烯 肠杆菌科 耐药机制 

分 类 号：R378[医药卫生—病原生物学]