局部晚期宫颈癌术前治疗方法选择  

Preoperative treatments for locally advanced cervical cancer

作　　者：狄文[1] 余敏华[1] DI Wen;YU Min-hua(Department of Obstetrics and Gynecology,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai Key Laboratory of Gynecologic Oncology,State Key Laboratory of Oncogenes and Related Genes,Shanghai Cancer Institute,Shanghai 200127,China)

机构地区：[1]上海交通大学医学院附属仁济医院妇产科,上海市妇科肿瘤重点实验室,癌基因及相关基因国家重点实验室,上海200127

出　　处：《中国实用妇科与产科杂志》2018年第11期1190-1193,共4页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：国家重点研发计划(2016YFC1302900);上海市重中之重临床重点学科--妇产科学(2017ZZ02016)

摘　　要：发展中国家宫颈癌的发病率及病死率逐年上升,其中,局部晚期宫颈癌因其治疗难度高、预后差也让妇科肿瘤学者面临巨大的挑战。由于存在个体化差异及区域卫生事业发展不均衡,局部晚期宫颈癌治疗方案的选择仍存在较大争议。在美国、加拿大等发达国家同步放化疗作为治疗局部晚期宫颈癌的标准治疗方案,而在欧洲、亚洲尤其是发展中国家和地区则选择辅助治疗后进行手术治疗。文章就国内外相关文献及指南对局部晚期宫颈癌术前治疗方法的选择进行介绍。The morbidity and mortality of cervical cancer in developing countries have been increasing year by year.Gynecologic oncologists face with huge challenges due to difficulty in treatment and poor prognosis of locally advanced cervical cancer.Owing to individual differences and uneven development of regional health services,the choices of treatment options for locally advanced cervical cancer remain controversial.Concurrent chemoradiotherapy is the standard treatment option for locally advanced cervical cancer in developed countries such as the United States and Canada.In Europe and Asia,especially in developing countries and regions,surgical treatment is selected after adjuvant therapy.This article describes the selection of preoperative treatments for locally advanced cervical cancer based on relevant literature and guidelines.

关 键 词：宫颈肿瘤 局部晚期 新辅助化疗 术前辅助放疗 外照射放疗 同步放化疗 近距离放疗 

分 类 号：R737.3[医药卫生—肿瘤]