产后抑郁患者血清P,E2,5-HT,NE和E水平在不同护理方法干预后的变化  

Levels of Serum P,E2,5-HT,NE and E in Patients with Postpartum Depression after Different Nursing Intervention

作　　者：郑蕊琳 毛红妮[2] ZHANG Rui -lin , MAO Hong- ni(Baoji People＇ s Hospital, Shaanxi Baiji 721000, China; Baoji Maternal and Child Health Care Hospital, Shaanxi Baiji 721000, China)

机构地区：[1]宝鸡市人民医院,陕西宝鸡721000 [2]宝鸡市妇幼保健院,陕西宝鸡721000

出　　处：《现代检验医学杂志》2018年第6期111-114,共4页Journal of Modern Laboratory Medicine

摘　　要：目的研究以家庭为中心的产科优质护理对产后抑郁患者血清孕酮(P)、雌二醇(E2)、5-羟色胺(5-HT)、去甲肾上腺素(NE)和肾上腺素(E)水平的影响。方法选择2016年1月～2017年12月宝鸡市人民医院收治的92例产后抑郁患者,随机分为两组。对照组采用常规的抑郁症护理方法,观察组采用以家庭为中心的产科优质护理方案。比较两组的血清P,E2,5-HT,NE和E水平。结果两组护理后的血清P,NE和E水平均明显降低,血清E2和5-HT水平均明显升高,差异均有统计学意义(t值分别为2.57,8.34,2.46,4.75,2.38;7.92,11.26,3.49,6.27,3.52,均P<0.05),且观察组明显优于对照组,差异有统计学意义(t值分别为4.27,5.14,3.98,4.76,5.92,均P<0.05);两组护理后SDS评分和SAS评分均明显降低,差异有统计学意义(t值分别为2.43,7.92;5.34,8.21,均P<0.05),且观察组更为明显,差异有统计学意义(t值分别为3.78,4.12,均P<0.05);观察组的有效率明显高于对照组,差异具有统计学意义(χ~2=4.42,P<0.05)。结论以家庭为中心的产科优质护理可以有效缓解产后抑郁患者的症状,改善其血清P,E2,5-HT,NE和E水平,值得应用推广。Objective To investigate the levels of serum P,E2,5-HT,NE and E in patients with postpartum depression after family centered high quality nursing intervention. Methods Selected 92 cases of patients with postpartum depression who were treated in Baoji People＇s Hospital from January 2016 to December 2017, and they were divided into two groups randomly. The control group was given routine nursing care for depression, while the observation group was given family-centered high-quality nursing care. The serum levels of P, E2,5-HT,NE and E were compared between the two groups. Results The serum levels of P, NE and E in the two groups were significantly lower, the serum levels of E2 and 5-HT were significantly higher, the difference was statistically significant （t= 2.57,8.34,2.46,4.75,2.38 and 7.92,11.26,3.49,6.27,3.52, all P〈0.05）, and the observation group was more obvious （t=4. 27,5.14,3. 98,4. 76,5. 92, P〈0. 05）. The SDS score and SAS score of the two groups were significantly lower after nursing, the difference was statistically significant （t=2.43,7.92 and 5.34,8.21,all P〈0.05） and the observation groupwas more obvious （t=3. 78,4.12, P〈0.05）. The effective rate was significantly higher than that of the control group, and the difference was statistically significant （x2 =4.42, P〈0.05）. Conclusion Family-centered high-quality obstetric care can effectively alleviate the symptoms of postpartum depression patients, and improve their serum P, E2,5-HT, NE and E levels, worthy of application.

关 键 词：孕酮 雌二醇 5-羟色胺 去甲肾上腺素 肾上腺素 产后抑郁 

分 类 号：R749.4[医药卫生—神经病学与精神病学] R392.11[医药卫生—临床医学]