化痰逐瘀消瘤汤对原发性脑瘤患者神经损伤及生活质量的影响  

Effect of phlegm stasis and tumor elimination decoction on nerve injury and quality of life in patients with primary brain tumors

作　　者：张遐智 刘学武 白吉庆[2] ZHANG Xia-zhi;LIU Xue-wu;BAI Ji-qing(Department of Encephalopathy,Luonan County Hospital of Traditional Chinese Medicine,Shangluo 726100,China;Science and Education Section,Shaanxi University of Traditional Chinese Medicine,Xianyang 712046,China)

机构地区：[1]陕西省商洛市洛南县中医医院脑病科,商洛726100 [2]陕西中医药大学科教科,咸阳712046

出　　处：《中国肿瘤临床与康复》2018年第11期1369-1372,共4页Chinese Journal of Clinical Oncology and Rehabilitation

基　　金：陕西省科技厅中药现代化项目(2012KTCL03-14)

摘　　要：目的探讨化痰逐瘀消瘤汤对原发性脑瘤患者神经损伤和生活质量的影响。方法选取2013年3月至2017年12月间洛南县中医医院收治的61例原发性脑瘤患者,采用随机数表法分为观察组31例和对照组30例。所有患者均采用止痛、抗炎、稳定电解质、营养支持等基础治疗及术后标准化放疗,观察组患者在此基础上采用化痰逐瘀消瘤汤治疗。比较两组患者的疗效、治疗前及治疗3个月后的神经功能和生活质量情况。结果观察组患者疗效优于对照组,差异有统计学意义(P <0. 05)。治疗前,两组患者卒中量表(NIHSS)评分比较,差异无统计学意义(P> 0. 05);治疗后,观察组患者的NIHSS评分低于对照组,两组患者NIHSS评分均低于治疗前,差异均有统计学意义(均P <0. 05)。治疗前,两组患者的卡氏(KPS)评分比较,差异无统计学意义(P> 0. 05);治疗后,观察组患者的KPS评分高于对照组,两组患者的KPS评分均高于治疗前,差异均有统计学意义(均P <0. 05)。结论化痰逐瘀消瘤汤利于提高经手术联合放疗治疗的原发性脑瘤患者的临床疗效,改善神经损伤程度,提高患者生活质量。Objective To explore the curative effect and the effect of phlegm stasis and tumor elimination decoction on nerve injury and quality of life in patients with primary brain tumors. Methods A total of 61 patients with primary brain tumors treated at Luonan County Hospital of Traditional Chinese Medicine from March 2013 to December 2017 were selected as the study subjects. They were divided into an observation group（ 31 patients） and a control group（ 30 patients）. All patients were given basic therapy such as pain relief,anti-inflammatory,stable electrolyte,nutritional support and standardized radiotherapy after surgery. On this basis,observation group was given phlegm stasis and tumor elimination decoction. The curative efficacy,neurological function and quality of life at 3 months before and after treatment were compared between two groups. Results The curative efficacy was better in the observation group than in the control group（ P〈0. 05）. Before treatment,there was no statistically significant difference in the national institutes of health stroke scale（ NIHSS） score between the two groups（ P〉0. 05）. After treatment,the NIHSS score was lower in the observation group than in the control group（ P〈0. 05）. The NIHSS score in two groups was lower after treatment than before treatment（ P〈0. 05）. Before treatment,there was no statistically significant difference in the Karnofsky performance status（ KPS） score between the two groups（ P〉0. 05）. After treatment,the KPS score was higher in the observation group than in the control group（ P〈0. 05）. The KPS score was higher in the two groups after treatment than before treatment（ all P〈0. 05）.Conclusion Phlegm stasis and tumor elimination decoction is helpful to improve the clinical treatment efficacy in patients with primary brain tumors who are treated with surgery combined with radiotherapy,and can improve nerve injury degree and quality of life.

关 键 词：原发性脑瘤 化痰逐瘀消瘤汤 神经损伤 生活质量 

分 类 号：R739.41[医药卫生—肿瘤]