PRF联合钛网在前牙美学区牙种植中应用的临床研究  

Research on PRF and titanium mesh using in dental implantation in aesthetic area

作　　者：冯靖[1] 宋砚斌[1] 蒋锋[1] 张双越[1] FENG Jing;SONG Yanbin;JIANG Feng;ZHANG Shuangyue(Department of Stomatology,Huaian First People＇s Hospital,Nanjing Medical University,Huaian 223300,China)

机构地区：[1]南京医科大学附属淮安第一医院.江苏省淮安市第一人民医院口腔科,江苏淮安223300

出　　处：《口腔医学》2018年第11期999-1002,共4页Stomatology

基　　金：淮安市科技局基金项目(HAS2015025)

摘　　要：目的将PRF联合钛网应用于前牙美学区牙种植和GBR术中,研究探讨其可行性和优势。方法选择前牙美学区单个牙种植需行同期GBR的患者(共13颗牙齿),随机分为2组,一组(对照组,6例牙齿)施行牙种植+单纯植骨+钛网覆盖术,另一组(PRF组,7例牙齿)施行牙种植+骨粉PRF混合后植骨+钛网PRF膜双层覆盖术;术后14 d评价伤口红肿和伤口愈合情况,术后4个半月行二期手术时切取部分新生骨行组织学观察。结果术后14 d,PRF组所有病例伤口基本无红肿,拆线后软组织伤口愈合良好;对照组有1例伤口无红肿,愈合良好,3例伤口红肿,拆线后伤口无裂开,2例伤口裂开,钛网暴露。组织学观察显示PRF组新生骨为较为成熟的板层骨,血管形成较为丰富,对照组新生骨骨小梁较为稀疏,结缔组织含量较多。结论 PRF联合钛网应用于前牙美学区种植GBR术中,可以减轻术后反应,促进软组织伤口愈合,加快新骨形成速度,具有较好的临床应用价值。Objective To investigate the clinical value of PRF and titanium mesh using in dental implantation in aesthetic area. Methods 13 cases with single tooth loss in aesthetic area were selected and divided into two groups. One group（ control group ,6 cases） was treated with dental implantation combined with pure artificial bone implantation covered by titanium mesh. The other group （ PRF group, 7 cases） was treated with dental implantation combined with artificial bone mixed with PRF implantation covered by titanium mesh and PRF membrane. Wound reaction and wound healing were evaluated at the 14th day after operation. After 4 and ahalf months after operation, newly formed bones were harvested for histological observation. Results Wounds of PRF group were well healed without swelling. In contrast, one case of control group had satisfying wound healing. Three cases had wound healing with swelling. Two cases had wound dehiscence with the exposure of titanium mesh. For histological observation, PRF group showed more mature bone formation with more amount of trabecular bones. Conclusion The using of PRF and titanium mesh can improve the newbone formation and reduce the tissue reaction, thus showing a satisfying clinical value in GBR procedure.

关 键 词：PRF 钛网 引导骨再生 

分 类 号：R783.4[医药卫生—口腔医学]