早期两路补液联合大黄芒硝散外敷腹部治疗急性胰腺炎的临床效果观察  

The Observation of the Clinical Efficacy of Early Two Way Rehydration Combined with Rhubarb and Mirabilite Powder for External Application of the Abdomen in Patients with Acute Pancreatitis

作　　者：黄泽辉[1] 林震群 周文博[1] 施宗明[1] 张毅娜[1] 张婷婷 苏玲玲[1] 王珊娜 黄国榕 陈熹[1] HUANG Zehui;LIN Zhenqun;ZHOU Wenbo(Zhangzhou Hospital of Traditional Chinese Medicine of Fujian Province,Zhangzhou 363000,China)

机构地区：[1]漳州市中医院,福建漳州363000

出　　处：《中外医学研究》2018年第33期3-5,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：2017年福建省卫生计生青年科研课题项目(项目编号:2017-2-66)

摘　　要：目的:观察及评价早期两路补液联合大黄芒硝散外敷腹部治疗急性胰腺炎的临床效果。方法:研究采用随机单盲对照法收集60例病例,并根据住院的先后顺序将所收集的病例随机化分为两组,每组30例,其中A组(两路补液+大黄芒硝散外敷腹部组),B组(两路补液组)。所有患者住院后予常规西药治疗。B组采用两路补液,一路为常规西药输液治疗,另一路为生理盐水补液治疗,补液总量按3 ml/(kg·h)计算,24 h后保留一路常规西药输液治疗。A组在B组基础上予大黄芒硝散外敷腹部1周。两组给予相应治疗后观察临床疗效。结果:A组与B组早期液体复苏达标率分别为96.7%、93.3%,差异无统计学意义(P>0.05)。A组临床疗效优于B组,差异有统计学意义(P<0.05)。A组患者腹痛/腹胀持续时间、白细胞升高持续时间、血清淀粉酶升高持续时间、患者住院时间均短于B组,差异均有统计学意义(P<0.05)。结论:早期两路补液联合大黄芒硝散外敷腹部治疗急性胰腺炎具有较好的临床疗效,安全性可靠,具有较好的临床应用前景。Objective：To observe and evaluate the clinical efficacy of early two way rehydration combined with rhubarb and mirabilite powder for external application of the abdomen in patients with acute pancreatitis.Method：Study by random single blind control method to collect 60 cases,according to the order of hospitalization,the collected cases were randomized into two groups,each group had 30 cases.Group A was treated by two way rehydration combined with rhubarb and mirabilite powder for external application of the abdomen, while group B received two way rehydration. All patients were given conventional western medicine after hospitalization. Group B was treated with two way rehydration, one way with conventional western medicine infusion, the other way with physiological saline infusion. The total amount of fluid infusion was calculated as 3 ml/（kg·h）,and keep one way with conventional western medicine infusion treatment after 24 hours.Group A was treated with rhubarb and mirabilite powder for external application of the abdomen for 1 weeks on the basis of group B. The two groups were given corresponding treatment to observe the clinical efficacy.Result：Group A and group B of early fluid resuscitation compliance rate was 96.7%, compared to 93.3%, there was no significant difference between them（P〈0.05）. The clinical efficacy of group A was better than that of group B（P0.05）. The duration of abdominal pain/abdominal distention in group A was shorter than that in group B（P〈0.01）. The duration of leukocyte increase in group A was shorter than that in group B（P0.05）. The duration of serum amylase increase in group A was shorter than that in group B（P0.05）. The length of stay of patients in group A was shorter than that in group B（P〈0.01）.Conclusion：Early two way rehydration combined with rhubarb and mirabilite powder for external application of the abdomen has good clinical therapeutic efficacy and reliable security in the treatment of patients with acute pancreatitis,so it has goo

关 键 词：两路补液 大黄芒硝散 急性胰腺炎 临床疗效 

分 类 号：R576[医药卫生—消化系统]