枸橼酸莫沙比利治疗反流性食管炎的效果  

Efficacy of mosapride citrate in the treatment of reflux esophagitis

作　　者：刘艾红 张波 LIU Ai-hong;ZHANG Bo(Shaanxi Rehabilitation Hospital,Xi＇an 710065;the Second Hospital of Yulin City,Yulin 719000,China)

机构地区：[1]陕西省康复医院,陕西西安710065 [2]榆林市第二医院,陕西榆林719000

出　　处：《临床医学研究与实践》2018年第34期47-48,共2页Clinical Research and Practice

摘　　要：目的探讨枸缘酸莫沙比利治疗反流性食管炎的临床效果。方法将2015年12月至2017年12月我院收治的74例反流性食管炎患者作为研究对象,随机分为观察组和对照组,每组37例。观察组患者采用枸缘酸莫沙比利治疗,对照组患者采用奥美拉唑治疗。比较两组患者的临床疗效及用药不良反应发生情况。结果观察组的治疗总有效率为97.3%,明显高于对照组的83.8%,差异具有统计学意义(P<0.05)。观察组患者用药后不良反应总发生率为8.1%,明显低于对照组的32.4%,差异具有统计学意义(P<0.05)。结论在反流性食管炎患者的临床治疗中,枸缘酸莫沙比利与奥美拉唑均有一定效果,但前者的临床疗效比后者更加理想,且安全性高,值得临床推广应用。Objective To investigate the clinical efficacy of mosapride citrate in the treatment of reflux esophagitis.Methods A total of 74 patients with reflux esophagitis admitted in our hospital from December 2015 to December 2017were randomly divided into observation group and control group, with 37 cases in each group. Patients in the observationgroup were treated with mosapride citrate, and patients in the control group were treated with omeprazole. The clinicalefficacy and adverse drug reactions in the two groups were compared. Results The total effective rate of treatment in theobservation group was 97.3% , which was significantly higher than 83.8% in the control group, the difference wasstatistically significant （P〈0.05）. The total incidence of adverse reactions in the observation group was 8.1%, which wassignificantly lower than 32.4% in the control group, the difference was statistically significant（P〈0.05）. Conclusion In theclinical treatment of patients with reflux esophagitis, mosapride and omeprazole have certain effects, but the clinicalefficacy of the former is more rational than the latter, and the safety is high, it is worthy of clinical application.

关 键 词：反流性食管炎 奥美拉唑 枸缘酸莫沙比利 

分 类 号：R571[医药卫生—消化系统]