射野分布对胰腺癌调强计划剂量的影响  

Effect of field arrangement on dosimetric of pancreatic cancer intensity-modulated plan

作　　者：温锦涛 程欢欢 王琳媛 张昆鹏[2] 王晓贞[1] WEN Jintao;CHENG Huanhuan;WANG Linyuan;ZHANG Kunpeng;WANG Xiaozhen(Department of Radiotherapy;Department of General Surgery,Xingtai People＇s Hospital,Xingtai 051031,China)

机构地区：[1]邢台市人民医院放疗科,河北邢台054031 [2]邢台市人民医院普外科,河北邢台054031

出　　处：《分子影像学杂志》2018年第4期469-472,共4页Journal of Molecular Imaging

摘　　要：目的比较胰腺癌5野调强放射治疗技术的3种射野布野方式对靶区剂量及其周围正常组织受量的差异,为临床选择放疗技术提供参考。方法选取9例胰腺癌患者,经CT扫描后在Eclipse8.6治疗计划系统中进行靶区勾画。对每位患者设计3种不同角度的5野调强计划。3种射野分布分别为,Ⅰ:5野均分共面布野;Ⅱ:Varian Eclipse计划系统角度自动优化布野;Ⅲ:物理师经验共面布野。在满足计划靶体积达到95%处方剂量时,比较靶区适形指数、均匀指数及周围正常组织受量之间的差异。结果 3种布野的调强计划,靶区适形指数及均匀指数差异无统计学意义;正常组织受量差异均无统计学意义(P>0.05)。结论 3种调强布野方式对于胰腺癌靶区及正常组织无明显剂量差异,但5野均分更简单直观,可减少布野时间,提高计划设计效率。Objective To compare the differences in doses distribution among three field arrangements of pancreatic cancerintensity-modulated plan on target volumes and surrounding normal tissues. Methods Nine patients with pancreatic cancerwere selected. The target volumes were delineated in the Varian Eclipse after CT scan. Three different field arrangements of 5-field Intensity-modulated plan were designed on each patient.The three field arrangements intensity-modulated plan were asfollows： Ⅰwas an average angle 5-filed coplanar plan, Ⅱwas the coplanar plan with the field arrangement from automaticoptimization of Eclipse planning system, the field arrangement of Ⅲ was from the experiences of physicists. All the planssatisfied the standard that 95 percent of target volume meet the prescribed dose. The differences of conformal index （CI）,heterogeneous index （HI） of target volumes and dose differences of surrounding normal tissues were compared. Results There was no significant difference in the conformal index and heterogeneous index of the target volumes among the threefield arrangements of intensity-modulated plans; The dose differences of normal tissures was not statistically significant.Conclusion There are no significant dose differences of pancreatic cancer’s target volumes and normal tissures among threefield arrangement of 5-field intensity-modulated plan.The average angle 5-filed coplanar plan is more simple, which canreduce the time of optimization process.

关 键 词：胰腺癌 放射治疗 调强放射治疗 角度优化 

分 类 号：R730.55[医药卫生—肿瘤] R735.9[医药卫生—临床医学]