中医药对腹部术后胃肠功能恢复Meta分析  

Meta Analysis of the Recovery of Gastrointestinal Function after Abdominal Operation by Traditional Chinese Medicine

作　　者：冯辉[1] 于庆生[2,3] 沈毅 张琦[2,3] 刘举达 周富海[2,3] FENG Hui;YU Qingsheng;SHEN Yi;ZHANG Qi;LIU Juda;ZHOU Fuhai(Anhui University of Traditional Chinese Medicine,Hefei 230038,Anhui,China;The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei 230031,Anhui,China;Surgery Institute of Anhui Provincial Academy of Traditional Chinese Medicine,Hefei 230031,Anhui,China)

机构地区：[1]安徽中医药大学,安徽合肥230038 [2]安徽中医药大学第一附属医院,安徽合肥230031 [3]安徽省中医药科学院外科研究所,安徽合肥230031

出　　处：《辽宁中医药大学学报》2018年第11期51-55,共5页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81573987;30973855;81403406);“十二五”国家临床重点专科建设项目(财社[2013]239号);“十二五”国家中医药管理局重点专科建设项目(国中医药医政发[2012]2号);“十二五”安徽省重点专科建设项目(卫中医药秘[2013]521号)

摘　　要：目的：评价中医药促进腹部术后胃肠功能恢复的临床疗效。方法：计算机检索PubMed、EMbase、the Cochrane Library、CBM、CNKI、VIP和Wanfang Data数据库,搜索中医药对腹部术后胃肠功能恢复相关的随机对照实验（RCT）,并进行Meta分析。结果：筛选符合纳入标准的文献19篇,共2712例患者。Meta分析显示,中医药联合常规治疗能够降低腹部术后肛门首次排气时间[MD为-15.28,95%CI（-18.80,-11.77）,P〈0.00001]、肛门首次排便时间[MD为-15.06,95%CI（-21.80,-8.33）,P〈0.0001]、肠鸣音恢复时间[MD为-9.28,95%CI（-11.66,-6.89）,P〈0.00001]和术后不良反应发生率[OR为0.38,95%CI（0.25,0.59）,P〈0.0001],提高有效率[OR为3.73,95%CI（2.09,6.66）,P〈0.00001]。结论：中医药联合常规治疗促进腹部术后胃肠功能恢复疗效较好,但由于纳入文献的质量不高,其临床疗效还需大样本、多中心、随机对照的试验进一步证实。Objective：To evaluate the clinical effect of traditional Chinese medicine on the recovery of gastrointestinal function after abdominal surgery. Methods：A computer literature search was conducted in PubMed,EMbase,the Cochrane Library,CBM,CNKI and VIP database and WanFang Data,search of traditional Chinese medicine related to recovery of gastrointestinal function after the abdominal surgery randomized controlled experiment（RCT）,a Meta analysis was performed. Results：A total of 19 articals were screened for inclusion criteria,a total of 2712 patients were involved. Meta analysis displayed that the traditional Chinese medicine combined conventional treatment can reduce abdominal postoperative anal exhaust time for the first time[MD=-15.28,95% CI（-18.80,-11.77）,P〈0.00001],the first time defecation anus[MD=15.06,95% CI（-21.80,-8.33）,P〈0.0001],bowel sounds recovery time[MD=-9.28,95% CI（-11.66,-6.89）,P〈0.00001]and the incidence of postoperative adverse reaction[OR=0.38,95% CI（0.25,0.59）,P〈0.0001],and improve the efficient[OR=3.73,95% CI（2.09,6.66）,P〈0.00001]. Conclusion：The traditional Chinese medicine combined with conventional treatment to promote abdominal postoperative gastrointestinal function recovered curative effect is good,but due to the quality is not high in literature,the clinical curative effect still need large sample,multicenter,randomized,controlled trial to further confirm.

关 键 词：中医药 腹部术后 胃肠功能 META分析 

分 类 号：R57[医药卫生—消化系统]