中药单体治疗急性胰腺炎的研究进展  

Research Progress of Chinese Pleiotropic Natural Products in Treatment of Acute Pancreatitis

作　　者：刘畅[1] 夏士林[1] 尚东[1] LIU Chang;XIA Shilin;SHANG Dong(Dalian Medical University,Dahan 116000,Liaoning,China)

机构地区：[1]大连医科大学附属第一医院大连医科大学中西医结合研究院

出　　处：《辽宁中医杂志》2018年第10期2232-2236,共5页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81373875,81072918);辽宁省省直医院改革重点临床科室诊疗能力建设项目(LNCCC-A03-2015)

摘　　要：急性胰腺炎（AP）是一种临床上常见急腹症,其中的重症胰腺炎,病情凶险、并发症多,甚至并发全身炎性反应综合征及多器官衰竭,导致死亡。AP的发病机制尚不明确,但随着对AP的探索逐渐深入,研究者发现中药在其治疗中较有好疗效,其中对中药单体治疗作用的研究成为热点。本文就中药单体治疗AP的主要机制与功能的实验研究进展进行综述,了解中药单体的作用,寻找更有效的治疗方法,为中药治疗AP机制研究方面提供思路。Acute pancreatitis（AP） is one of the common acute abdominal ailments in clinical practice,characterized by a critical condition and high mortality rate,which carries considerable morbidity and mortality. In severe cases,patients may develop into severe acute pancreatitis（SAP）,and present systemic inflammatory response syndrome（SIRS） or multiple organ failure（MOF）. Now its pathogenesis remains debatable,but the clinical value of Chinese medicine in AP treatment has attracted wide public attention. In rectent years,Chinese pleiotropic natural products were documented to be effective in AP treatment. This article aims to review studies about the mechanisms and functions of Chinese pleiotropic natural products,helping people to understand their value and gain insights in AP treatment.

关 键 词：急性胰腺炎 中药单体 治疗 机制 

分 类 号：R576[医药卫生—消化系统]