以纳米炭示踪乳腔镜下乳腺癌前哨淋巴结活检的临床研究  

Clinical Research of Endoscopic Sentinel Lymph Node Biopsy in Breast Cancer

作　　者：丁子晏 崔毕琦 孙丹平 徐姜玥 田莎 丁波泥[1] DING Zi-yan;CUI Bi-qi;SUN Dan-ping(the Xiangya Medical School,Central South University,Changsha 410000,China)

机构地区：[1]中南大学湘雅三医院,湖南长沙410000

出　　处：《中国实验诊断学》2018年第11期1897-1900,共4页Chinese Journal of Laboratory Diagnosis

基　　金：湖南省科技计划项目(2014SK3111)

摘　　要：目的探索以纳米炭为示踪剂,乳腺癌腔镜前哨淋巴结活检术的可行性及临床效果。方法收集2015年至2016年湘雅三医院收治的44例乳腺癌患者,随机抽签分为常规手术组24例,腔镜手术组20例,分析两组之间各指标的差别。结果常规手术组与腔镜手术组的基本情况、检出率、准确率、假阳性率无统计学差异(P>0.05),腔镜手术组手术时间较长,术中出血量较多(P<0.05)。结论以纳米炭为示踪剂行乳腺癌腔镜前哨淋巴结活检术有可行性,其临床效果与常规手术无明显差异,但腔镜操作延长了手术时间,增加了术中出血量,其手术技巧有待进一步提高。Objective To explore the feasibility and clinical effect of endoscopic sentinel lymph node biopsy（SLNB）with nano-carbon tracer in breast cancer.Methods 44 patients with breast cancer who underwent SLNB（including 20 patients with endoscopy and 24 with open operation）were analyzed by using nano-carbon tracer.Different index were observed between the two groups.Results There is no difference between the two groups in basic information,the successful rate of SLN detection,the accuracy rate,the false negative rate.In endoscopic group,the operative time was longer and the intra-operative blood loss was more than that in open operation group.Conclusion Endoscopic SLNB with nano-carbon tracer can obtain the similar clinical efficacy with traditional SLNB.However,the surgical technique of endoscopic SLNB remains to be further improved to reduce the prolonged operating time and the intra-operative blood loss.

关 键 词：纳米炭 腔镜手术 前哨淋巴结活检 

分 类 号：R737.9[医药卫生—肿瘤] R655.8[医药卫生—临床医学]