宫颈环形电切术与冷刀锥切术治疗宫颈上皮内瘤变的效果比较  

Comparison of cervical loop electrosurgical excision procedure and cold knife conization in the treatment of cervical intraepithelial neoplasia

作　　者：黄雪芳[1] 陈艳[1] 庞燕[1] 廖妮虹[1] Huang Xuefang;Chen Yan;Pang Yah;Liao Nihong(Guangdong Nongken Central Hospital,Zhanjiang 524002,China)

机构地区：[1]广东省农垦中心医院,湛江524002

出　　处：《临床医学》2018年第11期17-19,共3页Clinical Medicine

摘　　要：目的对比分析冷刀锥切术与宫颈环形电切术应用于宫颈上皮内瘤变的临床治疗效果。方法将2011年1月至2018年4月100例宫颈上皮内瘤变患者分为两组,每组50例。对照组给予冷刀锥切术治疗,观察组接受宫颈环形电切术治疗。比较两组疗效与并发症及随访HPV感染情况。结果观察组术中出血量少于对照组,手术时间与创面愈合时间短于对照组,差异有统计学意义(P <0. 05);两组低于术前活检级别、与术前活检一致、切缘阳性、浸润癌率比较,差异未见统计学意义(P> 0. 05)。观察组并发症发生率为12. 0%,显著低于对照组(32. 0%)(P <0. 05)。术后随访,对照组HPV感染率为12. 0%,明显高于观察组(2. 0%)(P <0. 05)。结论与冷刀锥切术比较,宫颈环形电切术应用于宫颈上皮内瘤变的临床治疗效果更佳,安全性高,复发率低,值得在临床中推广应用。Objective To compare and analyze the clinical effects of cold knife conization and loop electrosurgical excision procedure for cervical intraepithelial neoplasia. Methods One hundred cases of cervical intraepithelial neoplasia from February 2016 to March 2017 were divided into two groups,50 cases in each group. The control group was treated with cold knife conization,and the observation group was treated with loop electrosurgical excision procedure. The efficacy and complications of two groups were compared and HPV infection was followed up. Results The amount of intraoperative bleeding in the observation group was less than that of the control group,the time of operation and wound healing time were shorter,there were significanty differences（ P〈 0. 05）. The incidences of lower than the preoperative biopsy grade,the same preoperative biopsy,the positive margin of the cutting edge,and the infiltration cancer rates of the two groups had no significanty differences（ P〉 0. 05）. The incidence of complications in the observation group was 12%,which significantly lower than that in the control group（ 32. 0%,P〈 0. 05）. After operation,the infection rate of HPV in the control group was 12%,which was significantly higher than that（ 2%） in the observation group（ P〈 0. 05）. Conclusions Compared with the cold knife coning, cervical circular electrocision has better clinical effect on cervical intraepithelial neoplasia, and high safety, low recurrence rate. It is worthy of application in clinical practice.

关 键 词：宫颈环形电切术 宫颈上皮内瘤变 冷刀锥切术 并发症 

分 类 号：R737.33[医药卫生—肿瘤]