小脑发育不良性节细胞瘤/Lhermitte-Duclos病  

Dysplastic cerebellar gangliocytoma/Lhermitte-Duclos disease

作　　者：阎晓玲[1] YAN Xiao-ling(Department of Pathology,Tianjin Huanhu Hospital,Tianjin 300350,China)

机构地区：[1]天津市环湖医院病理科

出　　处：《中国现代神经疾病杂志》2018年第11期787-787,共1页Chinese Journal of Contemporary Neurology and Neurosurgery

摘　　要：小脑发育不良性节细胞瘤是临床罕见的良性小脑占位性病变,亦称为Lhermitte-Duclos病（LDD）,由发育不良的神经节细胞在原小脑结构层次中形成占位性病变,增大的神经节细胞主要位于内颗粒层,使小脑皮质增宽。小脑发育不良性节细胞瘤是常染色体显性遗传性疾病Cowden综合征在中枢神经系统的主要表现。目前尚未确定病变是肿瘤性还是错构性.Figure 1 Optical microscopy findings HE staining The internal granule cell layer of the cerebellum was filled with dysplastie ganglion cells （Panel la）. × 40 Focal magnified, medium to large ganglion cells with mild cytologic abnormalities could be seen （Panel lb）. × 200 Figure 2 Optical microscopy findings showed the nuclei of dysplastic ganglion cells were positive for NeuN. Immunohistoehemical staining （EnVision）×40.

关 键 词：小脑 疾病 调查结果 显微镜 房间 原子核 染色 面板 

分 类 号：R739.4[医药卫生—肿瘤]