大剂量^(99m)Tc-MDP治疗骨转移癌的临床研究  

Bolus injection of ^(99m)Tc-MDP in the treatment of bone metatasis

作　　者：孟昭信[1] 姜士杰[1] 魏学雅[1] 孙仲藩[1] 夏廷毅[1] 田爱萍[1] 杨雷[1] 金泉[1] 娄秀清[1] 王佐仁[1] 

机构地区：[1]空军总医院放射治疗科

出　　处：《空军总医院学报》1990年第1期6-8,共3页Journal of General Hospital of Air Force,PLA

摘　　要：作者利用放射性趋骨核素选择性地在骨转移灶异常浓聚显像原理,采用加大剂量的方法将常规剂量下用于核医学的诊断手段变为治疗手段。当大剂量^(99m)Tc—MDP注入人体后便在骨转移灶内形成内源性照射,使癌细胞直接受到辐射性杀伤。获得显著临床治疗效果,为骨转移癌的治疗开阔了新的途径。As strong affinity of 99mTc-MDP to metastasis lesions in bone could be observed on radioisotope diagnosis technique, a bolus injection was carried out in 20 patients with multiple bone metastasis. Endogenous irradiation was thus effected directly annihilating the cancer cells in bone metastasis. It is claimed that bolus injection of 99mTc-MDP is effective and safe for the relieve of pain in patients with multiple bone metastasis.

关 键 词：放射疗法 ^99MTC MDP 剂量 骨转移癌 

分 类 号：R738.1[医药卫生—肿瘤] R730.55[医药卫生—临床医学]